Evidence map›Paper›PMID 35558764›Full record

ArticleRSC advances2018

Tough and tissue-adhesive polyacrylamide/collagen hydrogel with dopamine-grafted oxidized sodium alginate as crosslinker for cutaneous wound healing.

Zhongxiang Bai, Weihua Dan, Guofei Yu, Yanjun Wang, Yining Chen, Yanping Huang, Changkai Yang, Nianhua Dan

Abstract read
In one paragraph

Article in RSC advances, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. RapidFrontiers in pharmacology · 2025
    Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Mussel-inspired biomaterials: From chemistry to clinic.Bioengineering & translational medicine · 2022
    Review
  12. Article
  13. Review
  14. Review
  15. Alginate and alginate composites for biomedical applications.Asian journal of pharmaceutical sciences · 2021
    Review
  16. Iranian journal of basic medical sciences · 2021
    Article
  17. Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Zhongxiang BaiResearch Center of Biomedical Engineering (Sichuan University) Chengdu 610065 China dwh5607@263.net.ORCID https://orcid.org/0000-0002-5135-5800
Weihua DanResearch Center of Biomedical Engineering (Sichuan University) Chengdu 610065 China dwh5607@263.net.
Guofei YuResearch Center of Biomedical Engineering (Sichuan University) Chengdu 610065 China dwh5607@263.net.
Yanjun WangState Key Laboratory of Polymer Materials Engineering (Sichuan University), Polymer Research Institute of Sichuan University Chengdu 610065 China.
Yining ChenResearch Center of Biomedical Engineering (Sichuan University) Chengdu 610065 China dwh5607@263.net.ORCID https://orcid.org/0000-0002-9501-5293
Yanping HuangResearch Center of Biomedical Engineering (Sichuan University) Chengdu 610065 China dwh5607@263.net.
Changkai YangResearch Center of Biomedical Engineering (Sichuan University) Chengdu 610065 China dwh5607@263.net.
Nianhua DanResearch Center of Biomedical Engineering (Sichuan University) Chengdu 610065 China dwh5607@263.net.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Natural collagen has good biocompatibility and ability to promote tissue regeneration; however, its low flexibility and easy degradation hinder its applications in wound repair. In this study, we synthesized a skin wound-repairing hydrogel with good bioactivity and high toughness and adhesion. Inspired by the good adhesion of natural mussels, dopamine was grafted onto oxidized sodium alginate to synthesize a new crosslinker (COA), which was introduced into the collagen/polyacrylamide (PAM-Col) double network to synthesize hydrogel. The morphological characterization of the hydrogel using scanning electron microscopy confirmed that the hydrogel formed a more chaotic interconnected structure after the introduction of COA. PAM-Col-COA hydrogel had good mechanical properties, skin tissue adhesion, water absorption, and sustained biological activity.

Identifiers

PMID35558764
PMCPMC9092085

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.