ArticleRSC advances2018
An iodine/DMSO-catalyzed sequential one-pot approach to 2,4,5-trisubstituted-1
Article in RSC advances, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
11 citing papers in PubMed, 1 synthesis or guideline pooled it.
- A scalable outpatient framework for BI-RADS 2-4B breast nodule management: an iodine-DMSO transdermal protocol.Frontiers in health services · 2026Pooled it
- Benzylic C-H Oxidation: Recent Advances and Applications in Heterocyclic Synthesis.Molecules (Basel, Switzerland) · 2024Review
- IRSC advances · 2024Review
- Oxidative Cross-Coupling of α-Amino Ketones with Alcohols Enabled by IThe Journal of organic chemistry · 2023Article
- Development of tissue paper-based chemosensor and demonstration for the selective detection of CuRSC advances · 2023Article
- Copper borate (CuBRSC advances · 2023Article
- IACS omega · 2022Article
- IRSC advances · 2021Article
- Article
- Insights into structural and physicochemical properties required for β-hematin inhibition of privileged triarylimidazoles.RSC medicinal chemistry · 2020Article
- Iodine-Mediated Oxidative Rearrangement of α,β-Unsaturated Diaryl Ketones: A Facile Access to 1,2-Diaryl Diketones.ACS omega · 2019Article
Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A sequential one-pot approach to 2,4,5-trisubstituted imidazoles has been developed from α-methylene ketones and aldehydes. This methodology employs air-moisture stable reaction conditions and an inexpensive iodine/DMSO system affording a diverse range of known and novel (substrate scope) 2,4,5-trisubstituted imidazoles in moderate to excellent yields. The iodine/DMSO system was extended to the domino convergent synthesis of two functionalized intermediates, benzil and benzaldehyde, to produce the final product.
Identifiers
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.