Evidence map›Paper›PMID 35558475›Full record

ArticleRSC advances2018

Synthesis, characterization and osteogenesis of phosphorylated methacrylamide chitosan hydrogels.

Huishang Yang, Shenggui Chen, Lei Liu, Chen Lai, Xuetao Shi

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in RSC advances, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 55% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 13 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Huishang YangNational Engineering Research Centre for Tissue Restoration and Reconstruction, School of Material Science and Engineering, South China University of Technology Guangzhou 510640 P. R. China shxt@scut.edu.cn.
Shenggui ChenNational Engineering Research Centre for Tissue Restoration and Reconstruction, School of Material Science and Engineering, South China University of Technology Guangzhou 510640 P. R. China shxt@scut.edu.cn.ORCID https://orcid.org/0000-0002-1683-1189
Lei LiuNational Engineering Research Centre for Tissue Restoration and Reconstruction, School of Material Science and Engineering, South China University of Technology Guangzhou 510640 P. R. China shxt@scut.edu.cn.
Chen LaiPeking University Shenzhen Institute, Peking University Shenzhen China.
Xuetao ShiNational Engineering Research Centre for Tissue Restoration and Reconstruction, School of Material Science and Engineering, South China University of Technology Guangzhou 510640 P. R. China shxt@scut.edu.cn.ORCID https://orcid.org/0000-0001-9919-8931
NIHR Surgical Reconstruction and Microbiology Research Centre · GBPeking University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Phosphorylated biopolymers can induce mineralization, mimic the process of natural bone formation, and have the potential as scaffolds for bone tissue engineering. 2-Methacryloyloxyethyl phosphorylcholine (MPC), a low cytotoxicity phosphorus source, is mainly applied in vascularization and promoting blood compatibility and has been less researched for bone repair. In this study, phosphorylated methacrylamide chitosan (PMAC) hydrogel was prepared by mixing methacrylamide chitosan (MAC) and different mass of MPC with photoinitiator under UV irradiation. A series characterization tests showed that PMAC hydrogels were successful prepared and had a pretty good mineralization ability. Moreover, human fetal osteoblastic (hFOB) cells cultured on PMAC hydrogels exhibited not only highly viability but also the enhanced ALP activity and calcium deposition. The PMAC hydrogels have great potential in bone tissue engineering applications.

Identifiers

PMID35558475
PMCPMC9088424
OpenAlexW2898276740

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.