Evidence map›Paper›PMID 35558459›Full record

ArticleRSC advances2018

Chemoenzymatic synthesis of polypeptides in neat 1,1,1,2-tetrafluoroethane solvent.

Isabel S Aguirre-Díaz, Carmina Montiel, Ismael Bustos-Jaimes, Yaocihuatl Medina-Gonzalez, Alberto Tecante, Miquel Gimeno

Open access · goldAbstract read
In one paragraph

Article in RSC advances, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 6 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 5 countries.

Isabel S Aguirre-DíazFacultad de Química, Depto. de Alimentos y Biotecnología, Universidad Nacional Autónoma de México (UNAM) CDMX Mexico mgimeno@unam.mx.
Carmina MontielFacultad de Química, Depto. de Alimentos y Biotecnología, Universidad Nacional Autónoma de México (UNAM) CDMX Mexico mgimeno@unam.mx.
Ismael Bustos-JaimesFacultad de Medicina, Depto. de Bioquímica, Universidad Nacional Autónoma de México (UNAM) CDMX Mexico.
Yaocihuatl Medina-GonzalezINPT, UPS, Laboratoire de Genie Chimique UMR CNRS 5503, Universite de Toulouse 4, Allee Emile Monso F-31030 Toulouse France.ORCID https://orcid.org/0000-0003-2859-8158
Alberto TecanteFacultad de Química, Depto. de Alimentos y Biotecnología, Universidad Nacional Autónoma de México (UNAM) CDMX Mexico mgimeno@unam.mx.
Miquel GimenoFacultad de Química, Depto. de Alimentos y Biotecnología, Universidad Nacional Autónoma de México (UNAM) CDMX Mexico mgimeno@unam.mx.ORCID https://orcid.org/0000-0003-2706-7048
Rede de Química e Tecnologia · PTMedicina · PLUniversité Fédérale de Toulouse Midi-Pyrénées · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chemoenzymatic polypeptide synthesis offers several advantages over chemical or other biological routes, however, the use of aqueous-based media suffers from reverse hydrolysis reactions that challenge peptide chain propagation. Herein, the protease from subtilisin Carlsberg biocatalyzed the synthesis of poly-l-PheOEt, poly-l-LeuOEt, and the copolymers poly-l-PheOEt-

Identifiers

PMID35558459
PMCPMC9088702
OpenAlexW2896692489

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.