Evidence map›Paper›PMID 35558343›Full record

ArticleThe journal of pediatric pharmacology and therapeutics : JPPT : the official journal of PPAG2022

Evaluation of Individualized Pain Plans for Children With Sickle Cell Disease Admitted for Vaso-occlusive Crisis at Riley Hospital for Children.

Alexandria M Arends, Anne Perez, Christina Wilder, Seethal A Jacob

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Article in The journal of pediatric pharmacology and therapeutics : JPPT : the official journal of PPAG, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

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0cells of the map it votes in
2citing papers in PubMed
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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

4 authors.

Alexandria M ArendsRiley Hospital for Children at Indiana University Health (AMA, SAJ), Indianapolis, IN.
Anne PerezRiley Hospital for Children at Indiana University Health (AMA, SAJ), Indianapolis, IN.
Christina WilderRiley Hospital for Children at Indiana University Health (AMA, SAJ), Indianapolis, IN.
Seethal A JacobRiley Hospital for Children at Indiana University Health (AMA, SAJ), Indianapolis, IN.

Funding

Telemedicine for Pediatric Sickle Cell Care in Medically Underserved CommunitiesK23HL143162 · NHLBI · INDIANA UNIVERSITY INDIANAPOLIS · PI JACOB, SEETHAL · 2021 to 2025
$919k
NHLBI NIH HHS K23 HL143162
6 · The paper itself

Abstract

objectiveVaso-occlusive crisis (VOC) is the most common problem reported by patients with sickle cell disease (SCD). The objective of this study was to evaluate the impact of individualized pain plans in pediatric patients with SCD admitted for VOC.

methodsThis was a pre- and post-study of patients with SCD admitted to Riley Hospital for Children for VOC from July 1, 2019, through July 1, 2020. The primary outcome was length of inpatient stay for VOC. Secondary outcomes included final pain score, days on scheduled opioids, days on breakthrough opioids, and average morphine milligram equivalents (MME) used per day.

resultsNine patients were included. The mean age was 16 years (range, 10-20 years). Key clinical findings were decreases in median [IQR] for final pain scores (7 [4.5-9] vs 6 [2.5-8], p = 0.396) and number of days of breakthrough opioid use (5 [3-8] vs 4 [2.5-5.5], p = 0.233). Following implementation of an individualized pain plan, there was an increase in median average MME per day (65.94 [53.1-97.7] vs 82.85 [41-114.3], p = 0.844). Median length of stay and days on scheduled opioids remained the same.

conclusionsThis study demonstrated that use of individualized pain plans in a small population of patients with SCD might result in decreased pain scores and decreased days on breakthrough opioids.

Indexed as

analgesics, opioidanemia, sickle cellchildhospitalizationlength of stayMMEpain management

Identifiers

PMID35558343
PMCPMC9088439

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.