Evidence map›Paper›PMID 35558281›Full record

ArticleRSC advances2018

Alteration of glycosylation in serum proteins: a new potential indicator to distinguish non-diabetic renal diseases from diabetic nephropathy.

Moyan Liu, Hanjie Yu, Dong Zhang, Qiuxia Han, Xiaoli Yang, Xiawei Liu, Jifeng Wang, Kun Zhang, Fuquan Yang, Guangyan Cai and 2 more

Open access · goldAbstract read
In one paragraph

Article in RSC advances, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.2field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 3 countries.

Moyan LiuDepartment of Nephrology, Chinese PLA General Hospital, Chinese PLA Institute of Nephrology, State Key Laboratory of Kidney Diseases, National Clinical Research Center of Kidney Diseases 28 Fuxing Road, Haidian District Beijing 100853 China hanyuzhu301@126.com zhangdong301@126.com.
Hanjie YuLaboratory for Functional Glycomics, College of Life Sciences, Northwest University Xi'an Shaanxi 710069 China.ORCID https://orcid.org/0000-0003-2684-8715
Dong ZhangDepartment of Nephrology, Chinese PLA General Hospital, Chinese PLA Institute of Nephrology, State Key Laboratory of Kidney Diseases, National Clinical Research Center of Kidney Diseases 28 Fuxing Road, Haidian District Beijing 100853 China hanyuzhu301@126.com zhangdong301@126.com.
Qiuxia HanDepartment of Nephrology, The First Affiliated Hospital of Zhengzhou University 1 East Jianshe Road Zhengzhou 450052 China.
Xiaoli YangDepartment of Nephrology, Chinese PLA General Hospital, Chinese PLA Institute of Nephrology, State Key Laboratory of Kidney Diseases, National Clinical Research Center of Kidney Diseases 28 Fuxing Road, Haidian District Beijing 100853 China hanyuzhu301@126.com zhangdong301@126.com.
Xiawei LiuLaboratory for Functional Glycomics, College of Life Sciences, Northwest University Xi'an Shaanxi 710069 China.
Jifeng WangThe Key Laboratory of Protein and Peptide Pharmaceuticals, Laboratory of Proteomics, Institute of Biophysics, Chinese Academy of Sciences Beijing 100101 China.
Kun ZhangLaboratory for Functional Glycomics, College of Life Sciences, Northwest University Xi'an Shaanxi 710069 China.
Fuquan YangThe Key Laboratory of Protein and Peptide Pharmaceuticals, Laboratory of Proteomics, Institute of Biophysics, Chinese Academy of Sciences Beijing 100101 China.
Guangyan CaiDepartment of Nephrology, Chinese PLA General Hospital, Chinese PLA Institute of Nephrology, State Key Laboratory of Kidney Diseases, National Clinical Research Center of Kidney Diseases 28 Fuxing Road, Haidian District Beijing 100853 China hanyuzhu301@126.com zhangdong301@126.com.
Xiangmei ChenDepartment of Nephrology, Chinese PLA General Hospital, Chinese PLA Institute of Nephrology, State Key Laboratory of Kidney Diseases, National Clinical Research Center of Kidney Diseases 28 Fuxing Road, Haidian District Beijing 100853 China hanyuzhu301@126.com zhangdong301@126.com.
Hanyu ZhuDepartment of Nephrology, Chinese PLA General Hospital, Chinese PLA Institute of Nephrology, State Key Laboratory of Kidney Diseases, National Clinical Research Center of Kidney Diseases 28 Fuxing Road, Haidian District Beijing 100853 China hanyuzhu301@126.com zhangdong301@126.com.
Chinese PLA General Hospital · CNNorthwest University · CNChinese Academy of Sciences · CNFirst Affiliated Hospital of Zhengzhou University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Diabetic nephropathy (DN) and nondiabetic renal disease (NDRD) are two major categories of renal diseases in diabetes mellitus patients. The clinical differentiation among them is usually not so clear and effective. In this study, sera from DN and NDRD patients were collected, and glycan profiles of serum proteins from DN and NDRD patients were investigated and compared by using lectin microarray and lectin blot. Then, altered glycoproteins were enriched by lectin coupled magnetic particle conjugate and characterized by LC-MS/MS. We found significant change in glycan patterns between DN and NDRD patients. In particular, the relative abundance of the glycopattern of Galβ1-3GalNAc which was identified by BPL (

Identifiers

PMID35558281
PMCPMC9090655
OpenAlexW2901353230

What OpenQuestion holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.