Evidence map›Paper›PMID 35558084›Full record

ArticleFrontiers in immunology2022

Sec-O-Glucosylhamaudol Inhibits RANKL-Induced Osteoclastogenesis by Repressing 5-LO and AKT/GSK3β Signaling.

Jinjin Cao, Ming-Xue Zhou, Xinyan Chen, Menglu Sun, Congmin Wei, Qisheng Peng, Zhou Cheng, Wanchun Sun, Hongbing Wang

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in immunology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.3field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Aqueous extract ofBiochemistry and biophysics reports · 2025
    Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Jinjin CaoPutuo People's Hospital, School of Life Sciences and Technology, Tongji University, Shanghai, China.
Ming-Xue ZhouDepartment of Neurology, Ruikang Hospital of Guangxi Traditional Chinese Medicine (TCM) University, Nanning, China.
Xinyan ChenPutuo People's Hospital, School of Life Sciences and Technology, Tongji University, Shanghai, China.
Menglu SunPutuo People's Hospital, School of Life Sciences and Technology, Tongji University, Shanghai, China.
Congmin WeiPutuo People's Hospital, School of Life Sciences and Technology, Tongji University, Shanghai, China.
Qisheng PengKey Laboratory of Zoonoses Research, Ministry of Education, Institute of Zoonosis, Jilin University, Changchun, China.
Zhou ChengPutuo People's Hospital, School of Life Sciences and Technology, Tongji University, Shanghai, China.
Wanchun SunKey Laboratory of Zoonoses Research, Ministry of Education, Institute of Zoonosis, Jilin University, Changchun, China.
Hongbing WangPutuo People's Hospital, School of Life Sciences and Technology, Tongji University, Shanghai, China.
Tongji University · CNJilin University · CNGuangxi University of Chinese Medicine · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Sec-O-glucosylhamaudol (SOG), an active flavonoid compound derived from the root of

Indexed as

Bone ResorptionOsteogenesisAnimalsGlycogen Synthase Kinase 3 betaMiceNFATC Transcription FactorsProto-Oncogene Proteins c-aktGlycogen Synthase Kinase 3 betaNFATC Transcription FactorsProto-Oncogene Proteins c-akt5-lipoxygenaseAKTGSK3βNFATc1osteoclastsSec-O-glucosylhamaudol

Identifiers

PMID35558084
PMCPMC9087042
OpenAlexW4285741261

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.