Evidence map›Paper›PMID 35558082›Full record

ArticleFrontiers in immunology2022

Role of Programmed Cell Death Protein-1 and Lymphocyte Specific Protein Tyrosine Kinase in the Aryl Hydrocarbon Receptor- Mediated Impairment of the IgM Response in Human CD5

Jiajun Zhou, Lance K Blevins, Robert B Crawford, Norbert E Kaminski

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.2field-weighted citation impact, top 55% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Jiajun ZhouDepartment of Microbiology & Molecular Genetics, Michigan State University, East Lansing, MI, United States.
Lance K BlevinsInstitute of Integrative Toxicology, Michigan State University, East Lansing, MI, United States.
Robert B CrawfordInstitute of Integrative Toxicology, Michigan State University, East Lansing, MI, United States.
Norbert E KaminskiInstitute of Integrative Toxicology, Michigan State University, East Lansing, MI, United States.
Michigan State University · US

Funding

VOLATILE ORGANIC CONTAMINANTS--QUANTIFYING THEIR MOVEMENT IN THE UNSATURATED ZONEP42ES004911 · NIEHS · MICHIGAN STATE UNIVERSITY · PI Brian P. Johnson · 1989 to 2026
$64.9M
6 · The paper itself

Abstract

Innate-like B cells (ILBs) are a heterogeneous population B cells which participate in innate and adaptive immune responses. This diverse subset of B cells is characterized by the expression of CD5 and has been shown to secrete high levels of immunoglobulin M (IgM) in the absence of infection or vaccination. Further, CD5

Indexed as

Basic Helix-Loop-Helix ProteinsB-LymphocytesLymphocyte Specific Protein Tyrosine Kinase p56(lck)Polychlorinated DibenzodioxinsProgrammed Cell Death 1 ReceptorReceptors, Aryl HydrocarbonHumansImmunoglobulin MAHR protein, humanBasic Helix-Loop-Helix ProteinsImmunoglobulin MLCK protein, humanLymphocyte Specific Protein Tyrosine Kinase p56(lck)PDCD1 protein, humanPolychlorinated DibenzodioxinsProgrammed Cell Death 1 ReceptorReceptors, Aryl HydrocarbonAhR (aryl hydrocarbon receptor)IFNgammaIgMinnate-like B cellsLckPD1 (programmed cell death protein 1)TCDD

Identifiers

PMID35558082
PMCPMC9088000
OpenAlexW4225007546

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.