Evidence map›Paper›PMID 35557876›Full record

ArticleRSC advances2018

Cholesterol-sensing role of phenylalanine in the interaction of human islet amyloid polypeptide with lipid bilayers.

Ruijie Hao, Yang Li, Liping Guan, Tong Lu, Feihong Meng, Chunyu Wang, Fei Li

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in RSC advances, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.1field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Ruijie HaoState Key Laboratory of Supramolecular Structure and Materials, Jilin University 2699 Qianjin Avenue Changchun 130012 P. R. China feili@jlu.edu.cn.
Yang LiState Key Laboratory of Supramolecular Structure and Materials, Jilin University 2699 Qianjin Avenue Changchun 130012 P. R. China feili@jlu.edu.cn.
Liping GuanState Key Laboratory of Supramolecular Structure and Materials, Jilin University 2699 Qianjin Avenue Changchun 130012 P. R. China feili@jlu.edu.cn.
Tong LuState Key Laboratory of Supramolecular Structure and Materials, Jilin University 2699 Qianjin Avenue Changchun 130012 P. R. China feili@jlu.edu.cn.
Feihong MengState Key Laboratory of Supramolecular Structure and Materials, Jilin University 2699 Qianjin Avenue Changchun 130012 P. R. China feili@jlu.edu.cn.
Chunyu WangState Key Laboratory of Supramolecular Structure and Materials, Jilin University 2699 Qianjin Avenue Changchun 130012 P. R. China feili@jlu.edu.cn.
Fei LiState Key Laboratory of Supramolecular Structure and Materials, Jilin University 2699 Qianjin Avenue Changchun 130012 P. R. China feili@jlu.edu.cn.ORCID https://orcid.org/0000-0003-0490-7411
Jilin University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The interactions between hIAPP and the pancreatic β-cells are associated with β-cell death in type II diabetes. Cholesterol modulates hIAPP-membrane interaction and hIAPP aggregation. The molecular mechanism underlying this is not well understood. Here we explore the cholesterol-sensing role of F15 in the interactions of hIAPP and hIAPP

Identifiers

PMID35557876
PMCPMC9091444
OpenAlexW2902279907

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.