Evidence map›Paper›PMID 35557855›Full record

ArticleRSC advances2018

An expeditious and efficient bromomethylation of thiols: enabling bromomethyl sulfides as useful building blocks.

Carolina Silva-Cuevas, Ehecatl Paleo, David F León-Rayo, J Armando Lujan-Montelongo

Open access · goldAbstract read
In one paragraph

Article in RSC advances, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 51% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 11 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Carolina Silva-CuevasDepartamento de Química, Centro de Investigación y de Estudios Avanzados (Cinvestav) Av. Instituto Politécnico Nacional 2508, San Pedro Zacatenco 07360 Ciudad de México México jalujanm@cinvestav.mx.
Ehecatl PaleoFacultad de Ciencias, Universidad Nacional Autónoma de México, Ciudad Universitaria 04510 Ciudad de México México.
David F León-RayoDepartamento de Química, Centro de Investigación y de Estudios Avanzados (Cinvestav) Av. Instituto Politécnico Nacional 2508, San Pedro Zacatenco 07360 Ciudad de México México jalujanm@cinvestav.mx.
J Armando Lujan-MontelongoDepartamento de Química, Centro de Investigación y de Estudios Avanzados (Cinvestav) Av. Instituto Politécnico Nacional 2508, San Pedro Zacatenco 07360 Ciudad de México México jalujanm@cinvestav.mx.ORCID https://orcid.org/0000-0002-5651-8955
Centro de Investigación y de Estudios Avanzados del Instituto Politécnico Nacional · MXUniversidad Nacional Autónoma de México · MX

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A facile and highly efficient method for the bromomethylation of thiols, using paraformaldehyde and HBr/AcOH, has been developed, which advantageously minimizes the generation of highly toxic byproducts. The preparation of 22 structurally diverse α-bromomethyl sulfides illustrates the chemo-tolerant applicability while bromo-lithium exchange and functionalization sequences, free radical reductions, and additions of the title compounds demonstrate their synthetic utility.

Identifiers

PMID35557855
PMCPMC9092473
OpenAlexW2853370774

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.