ArticleFrontiers in endocrinology2022
Investigation and Application of Risk Factors of Macrosomia Based on 10,396 Chinese Pregnant Women.
Article in Frontiers in endocrinology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed, 12 citations in OpenAlex.
- Association between maternal serum RANKL and adverse birth outcomes: a prospective cohort study.Annals of medicine · 2026Article
- Identifying critical windows for macrosomia prevention: a study on the association between phase-specific dynamic BMI changes and macrosomia risk.Frontiers in endocrinology · 2026Article
- Mediating effects of maternal blood lipids and glucose on the relationship between pre-pregnancy body mass index and newborn birth weight in women with gestational diabetes mellitus.BMC pregnancy and childbirth · 2025Article
- Maternal Gut Microbiota in Gestational Diabetes Mellitus and Fetal Macrosomia: Is There an Association?Biomedicines · 2025Article
- Trends of Large for Gestational Age and Macrosomia and Their Mediating Effect on the Association Between Diabetes Mellitus and Obstetric Hemorrhage.Maternal & child nutrition · 2025Article
- Association Between Maternal Creatinine to Body Weight Ratio and Small/Large for Gestational Age Newborns Among 11,734 Chinese Women.Journal of epidemiology and global health · 2025Observational
- Maternal obesity and the incidence of large-for-gestational-age newborns in isolated hypothyroxinemia pregnancies: a comparative cohort study.Reproductive biology and endocrinology : RB&E · 2025Article
- An Increased Plasma D-Dimer Levels During Different Stages of Normal and Complicated Pregnancies Among Women in Bisha, Saudi Arabia.Journal of blood medicine · 2025Article
- Assessing the risk factors and establishing multivariable prediction models for singleton macrosomia.Frontiers in medicine · 2025Article
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objective: The objective of this study was to examine the association of fetal macrosomia with maternal D-dimer and blood lipid levels, and explore whether D-dimer and blood lipids, either alone or in combination with traditional risk factors at hospital birth, could be used to predict subsequent delivery of macrosomia. Methods: From April 2016 to March 2017, 10,396 women with singleton pregnancy giving birth at around 28-41 weeks of gestation were recruited into the present study. D-dimer and blood lipid levels were measured at hospital admission; and data on birth outcomes were obtained from hospital records. Results: Multivariate logistic regression analysis showed that D-dimer, triglyceride and HDL-C levels were significantly associated with risk of macrosomia independent of traditional risk factors (for D-dimer: adjusted OR: 1.33, 95% CI, 1.23-1.43; for triglyceride: adjusted OR: 1.14, 95% CI, 1.05-1.23; for HDL-C: adjusted OR: 0.35, 95% CI, 0.24-0.51, all Conclusion: Our study demonstrates that maternal D-dimer, triglyceride, and HDL-C levels before hospital birth could be significant and independent of risk factors of fetal macrosomia. Therefore, combining D-dimer and blood lipid levels with traditional risk factors might improve the ability to predict macrosomia in gestational diabetes mellitus and normal pregnancies.
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