Evidence map›Paper›PMID 35557655›Full record

ArticleACS omega2022

Amphotericin B Tamed by Salicylic Acid.

Yuming Yu, Peng Chen, Ming Gao, Wei Lan, Shijun Sun, Ziwei Ma, Rome Sultani, Yincang Cui, Muhammad Naveed Umar, Sher Wali Khan and 3 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in ACS omega, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 12 citations in OpenAlex.

  1. Antifungal mechanism against Candida albicans and antitumor activity of phenazines produced by Pseudomonas sp. strain DH.International microbiology : the official journal of the Spanish Society for Microbiology · 2026
    Article
  2. Review
  3. Article
  4. Aspirin Combined with Antifungal Drugs SuppressesJournal of microbiology and biotechnology · 2025
    Article
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 5 institutions in 2 countries.

Yuming YuState Key Laboratory of Chemistry and Utilization of Carbon-Based Energy Resources; College of Chemistry, Xinjiang University, Urumqi 830017, Xinjiang, P. R. China.
Peng ChenState Key Laboratory of Chemistry and Utilization of Carbon-Based Energy Resources; College of Chemistry, Xinjiang University, Urumqi 830017, Xinjiang, P. R. China.
Ming GaoState Key Laboratory of Chemistry and Utilization of Carbon-Based Energy Resources; College of Chemistry, Xinjiang University, Urumqi 830017, Xinjiang, P. R. China.
Wei LanState Key Laboratory of Chemistry and Utilization of Carbon-Based Energy Resources; College of Chemistry, Xinjiang University, Urumqi 830017, Xinjiang, P. R. China.ORCID https://orcid.org/0000-0003-1825-2823
Shijun SunState Key Laboratory of Chemistry and Utilization of Carbon-Based Energy Resources; College of Chemistry, Xinjiang University, Urumqi 830017, Xinjiang, P. R. China.
Ziwei MaState Key Laboratory of Chemistry and Utilization of Carbon-Based Energy Resources; College of Chemistry, Xinjiang University, Urumqi 830017, Xinjiang, P. R. China.
Rome SultaniState Key Laboratory of Chemistry and Utilization of Carbon-Based Energy Resources; College of Chemistry, Xinjiang University, Urumqi 830017, Xinjiang, P. R. China.
Yincang CuiPhysics and Chemistry Detect Center, Xinjiang University, Urumqi 830017, Xinjiang P. R. China.
Muhammad Naveed UmarDepartment of Chemistry, University of Malakand, Chakdara, Dir (L), Khyber Pakhtunkhwa 18800, Pakistan.
Sher Wali KhanDepartment of Chemistry, Shaheed Benazir Bhutto University Sheringal, Dir (U), Khyber Pakhtunkhwa 18800, Pakistan.
Xiaodong CaiDepartment of Neurosurgery, The First Affiliated Hospital of Shenzhen University, Shenzhen Second People's Hospital, Shenzhen 518026, China.
Zhenjiang LiangPneumology Department, Shenzhen Children's Hospital, Shenzhen 518026, China.
Hui TanPneumology Department, Shenzhen Children's Hospital, Shenzhen 518026, China.
Xinjiang University · CNShenzhen Children's Hospital · CNShenzhen Second People's Hospital · CNShaheed Benazir Bhutto University · PKUniversity of Malakand · PK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Although Amphotericin B (AmB) is considered as the "gold standard" treatment for deep fungal infections, owing to its excellent antifungal effect, it often causes severe hemolytic toxicity and nephrotoxicity, which limits its clinical use. We designed and synthesized AmB derivatives by attaching salicylic acid (SA) to the carboxyl group and confirmed their structures using

Identifiers

PMID35557655
PMCPMC9088917
OpenAlexW4224302110

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.