ArticleFrontiers in neurology2022
Sensitivity of Diffusion MRI to White Matter Pathology: Influence of Diffusion Protocol, Magnetic Field Strength, and Processing Pipeline in Systemic Lupus Erythematosus.
Article in Frontiers in neurology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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7 citing papers in PubMed, 10 citations in OpenAlex.
- Microstructural alterations in brain tissue of ME/CFS and long COVID using diffusion tensor imaging and diffusion kurtosis imaging.Frontiers in medicine · 2026Article
- Denoising Improves Cross-Scanner and Cross-Protocol Test-Retest Reproducibility of Diffusion Tensor and Kurtosis Imaging.Human brain mapping · 2025Article
- Impact of truncating diffusion MRI scans on diffusional kurtosis imaging.Magma (New York, N.Y.) · 2024Article
- Topological structural characteristics in patients with systemic lupus erythematosus with and without neuropsychiatric symptoms.Lupus science & medicine · 2024Article
- Comparison of distortion correction preprocessing pipelines for DTI in the upper limb.Magnetic resonance in medicine · 2024Article
- Optimization and validation of the DESIGNER preprocessing pipeline for clinical diffusion MRI in white matter aging.Imaging neuroscience (Cambridge, Mass.) · 2024Article
- MRI BrainAGE demonstrates increased brain aging in systemic lupus erythematosus patients.Frontiers in aging neuroscience · 2023Article
Corrections and comments
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Authors and funding
8 authors at 4 institutions in 3 countries.
Funding
Abstract
There are many ways to acquire and process diffusion MRI (dMRI) data for group studies, but it is unknown which maximizes the sensitivity to white matter (WM) pathology. Inspired by this question, we analyzed data acquired for diffusion tensor imaging (DTI) and diffusion kurtosis imaging (DKI) at 3T (3T-DTI and 3T-DKI) and DTI at 7T in patients with systemic lupus erythematosus (SLE) and healthy controls (HC). Parameter estimates in 72 WM tracts were obtained using TractSeg. The impact on the sensitivity to WM pathology was evaluated for the diffusion protocol, the magnetic field strength, and the processing pipeline. Sensitivity was quantified in terms of Cohen's
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