Evidence map›Paper›PMID 35555921›Full record

SynthesisMycoses2022

Global prevalence and subgroup analyses of coronavirus disease (COVID-19) associated Candida auris infections (CACa): A systematic review and meta-analysis.

Narges Vaseghi, Joobin Sharifisooraki, Hossein Khodadadi, Sanam Nami, Fatemeh Safari, Fatemeh Ahangarkani, Jacques F Meis, Hamid Badali, Hamid Morovati

Open access · greenAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Mycoses, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed, 4 pooled it
6.0field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed, 4 syntheses or guidelines pooled it, 63 citations in OpenAlex.

  1. Pooled it
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  9. Genetic Confirmation of Clonal Spread ofJournal of fungi (Basel, Switzerland) · 2025
    Article
  10. Article
  11. First report ofEmerging microbes & infections · 2024
    Article
  12. TheHealth science reports · 2024
    Article
  13. Article
  14. Current global status of Candida auris an emerging multidrug-resistant fungal pathogen: bibliometric analysis and network visualization.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2024
    Article
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  18. An Autochthonous SusceptibleJournal of fungi (Basel, Switzerland) · 2023
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  19. First report of Candida auris in Romania: clinical and molecular aspects.Antimicrobial resistance and infection control · 2023
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 8 institutions in 4 countries.

Narges VaseghiDepartment of Pathobiology, Science and Research Branch, Islamic Azad University, Tehran, Iran.
Joobin SharifisoorakiHealth Reproductive Research Center, Sari Branch, Islamic Azad University, Sari, Mazandaran, Iran.
Hossein KhodadadiDepartment of Parasitology and Mycology, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran.ORCID https://orcid.org/0000-0001-9507-8764
Sanam NamiDepartment of Medical Mycology and Parasitology, School of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran.ORCID https://orcid.org/0000-0001-9187-5555
Fatemeh SafariDepartment of Microbiology, Falavarjan Branch, Islamic Azad University, Isfahan, Iran.ORCID https://orcid.org/0000-0001-9509-5708
Fatemeh AhangarkaniAntimicrobial Resistance Research Center, Communicable Diseases Institute, Mazandaran University of Medical Sciences, Sari, Iran.ORCID https://orcid.org/0000-0002-3629-7446
Jacques F MeisDepartment of Medical Microbiology and Infectious Diseases, Canisius-Wilhelmina Hospital, Nijmegen, The Netherlands.ORCID https://orcid.org/0000-0003-3253-6080
Hamid BadaliDepartment of Molecular Microbiology & Immunology/South Texas Center for Emerging Infectious Diseases, The University of Texas at San Antonio, San Antonio, Texas, USA.ORCID https://orcid.org/0000-0002-6010-8414
Hamid MorovatiDepartment of Parasitology and Mycology, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran.ORCID https://orcid.org/0000-0002-3569-0035
Shiraz University of Medical Sciences · IRIslamic Azad University, Isfahan · IRIslamic Azad University Sari Branch · IRIslamic Azad University, Science and Research Branch · IRMazandaran University of Medical Sciences · IRRadboud University Nijmegen · NLTabriz University of Medical Sciences · IRTexas Center for Infectious Disease · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIncreased hospitalisation rates in the Coronavirus disease 19 (COVID-19) era lead to a new wave of hospital-acquired infections such as emerging multidrug-resistant Candida auris. We aimed to evaluate and estimate the global prevalence of coronavirus-associated C. auris infection (CACa).

methodsWe searched related databases between December 2019 and April 2022 for studies that reported data about CACa. Meta-analysis was performed using MedCalc software version 20.104 according to the DerSimonian and Laird method applying the random-effects model. We evaluated heterogeneity using the χ

resultsOur meta-analysis includes ten eligible studies, including 1942 patients hospitalised with COVID-19; 129 were C. auris cases. The overall pooled prevalence of CACa was estimated at 5.7%. The mortality rate of CACa was estimated at 67.849%. Hypertension was the most prevalent comorbidity (59.374%), followed by diabetes mellitus (52.898%) and cardiovascular diseases (31.392%). Men with a prevalence rate of 80.012% were 3.27 (OR) times more prone to getting infected by C. auris.

conclusionWe concluded that the prevalence of C. auris infections decreased during the COVID-19 pandemic and the prevalence gradient changed from Asia to America. Unfortunately, there are many descriptive studies with duplicate content in the field of epidemiology of C. auris infections which are increasing every day. We suggest further non-descriptive studies to accurately establish the cause-and-effect relationships between C. auris and COVID-19 infections.

Indexed as

COVID-19PandemicsAntifungal AgentsCandidaCandida aurisCandidiasis, InvasiveHumansMalePrevalenceAntifungal AgentsCandida auriscoronavirus disease 19 (COVID-19)COVID associated infectionsprevalencerisk factorsSARS-CoV-2

Identifiers

PMID35555921
PMCPMC9347948
OpenAlexW4280499270

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.