Evidence map›Paper›PMID 35554865›Full record

ArticleProbiotics and antimicrobial proteins2022

Levilactobacillus brevis KU15151 Inhibits Staphylococcus aureus Lipoteichoic Acid-Induced Inflammation in RAW 264.7 Macrophages.

Won-Ju Kim, Hyung-Seok Yu, Na-Kyoung Lee, Hyun-Dong Paik

Abstract read
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In one paragraph

Article in Probiotics and antimicrobial proteins, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.5field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 11 citations in OpenAlex.

  1. Intestinal Epithelial-Protective Effects ofJournal of microbiology and biotechnology · 2026
    Article
  2. Review
  3. Article
  4. Heat-KilledJournal of microbiology and biotechnology · 2025
    Article
  5. Heat-KilledMicroorganisms · 2024
    Article
  6. Lipoteichoic Acid fromNutrients · 2024
    Article
  7. Heat-Treated ParaprobioticJournal of microbiology and biotechnology · 2024
    Article
  8. Anti-inflammatory activities ofFood science and biotechnology · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Won-Ju KimDepartment of Food Science and Biotechnology of Animal Resources, Konkuk University, Seoul, 05029, Republic of Korea.
Hyung-Seok YuDepartment of Food Science and Biotechnology of Animal Resources, Konkuk University, Seoul, 05029, Republic of Korea.
Na-Kyoung LeeDepartment of Food Science and Biotechnology of Animal Resources, Konkuk University, Seoul, 05029, Republic of Korea.
Hyun-Dong PaikDepartment of Food Science and Biotechnology of Animal Resources, Konkuk University, Seoul, 05029, Republic of Korea. hdpaik@konkuk.ac.kr.ORCID 0000-0001-9891-7703
Konkuk University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Inflammation is a host defense response to harmful agents, such as pathogenic invasion, and is necessary for health. Excessive inflammation may result in the development of inflammatory disorders. Levilactobacillus brevis KU15151 has been reported to exhibit probiotic characteristics and antioxidant activities, but the effect of this strain on inflammatory responses has not been determined. The present study aimed to investigate the anti-inflammatory potential of L. brevis KU15151 in Staphylococcus aureus lipoteichoic acid (aLTA)-induced RAW264.7 macrophages. Treatment with L. brevis KU15151 reduced the production of nitric oxide and prostaglandin E

Indexed as

LipopolysaccharidesStaphylococcus aureusAnimalsInflammationInterleukin-6LactobacillusMacrophagesMiceNF-kappa BNitric OxideNitric Oxide Synthase Type IIRAW 264.7 CellsTeichoic AcidsInterleukin-6Lipopolysaccharideslipoteichoic acidNF-kappa BNitric OxideNitric Oxide Synthase Type IITeichoic AcidsAnti-inflammatory effectLevilactobacillus brevisMAPK signaling pathwayNF-kappaB signaling pathwayRAW 264.7 cell

Identifiers

PMID35554865
OpenAlexW4280564116

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.