Evidence map›Paper›PMID 35553000›Full record

SynthesisClinical reviews in allergy & immunology2022

Infections or Vaccines Associated with Finkelstein-Seidlmayer Vasculitis: Systematic Review.

Gabriel Bronz, Céline Betti, Pietro O Rinoldi, Lisa Kottanattu, Mario G Bianchetti, Danilo Consolascio, Marcel M Bergmann, Gregorio P Milani, Benedetta Terziroli Beretta Piccoli, Sebastiano A G Lava

Open access · hybridAbstract readSystematic Review
In one paragraph

Synthesis in Clinical reviews in allergy & immunology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.8field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 5 citations in OpenAlex.

  1. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 6 institutions in 3 countries.

Gabriel BronzPediatric Institute of Southern Switzerland, Ente Ospedaliero Cantonale, Bellinzona, Switzerland.
Céline BettiPediatric Institute of Southern Switzerland, Ente Ospedaliero Cantonale, Bellinzona, Switzerland.
Pietro O RinoldiPediatric Institute of Southern Switzerland, Ente Ospedaliero Cantonale, Bellinzona, Switzerland.
Lisa KottanattuPediatric Institute of Southern Switzerland, Ente Ospedaliero Cantonale, Bellinzona, Switzerland.
Mario G BianchettiFaculty of Biomedical Sciences, Università Della Svizzera Italiana, Lugano, Switzerland.
Danilo ConsolascioFamily Medicine, Faculty of Biomedical Sciences, Università Della Svizzera Italiana, Lugano, Switzerland.
Marcel M BergmannCentro Pediatrico del Mendrisiotto, Mendrisio, Switzerland.
Gregorio P MilaniPediatric Unit, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.
Benedetta Terziroli Beretta PiccoliFaculty of Biomedical Sciences, Università Della Svizzera Italiana, Lugano, Switzerland. benedetta.terziroli@hin.ch.ORCID http://orcid.org/0000-0001-5004-5029
Sebastiano A G LavaPediatric Cardiology Unit, Department of Pediatrics, Centre Hospitalier Universitaire Vaudois and University of Lausanne, Lausanne, Switzerland.
Ente Ospedaliero Cantonale · CHUniversità della Svizzera italiana · CHEpatocentro Ticino · CHGreat Ormond Street Hospital · GBUniversity Hospital of Geneva · CHUniversity of Milan · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Finkelstein-Seidlmayer vasculitis, also referred to as acute hemorrhagic edema of young children, is a rare small-vessel leukocytoclastic vasculitis. This condition is skin-limited, mainly affects infants up to 2 years of age and spontaneously remits. It has been suggested that an infection or a vaccine precede (by ≤ 14 days) this vasculitis. To better understand the interplay between infections or vaccines and Finkelstein-Seidlmayer vasculitis, we utilized the data contained in the Acute Hemorrhagic Edema BIbliographic Database AHEBID. The database, initiated in 2019, is being regularly updated, encompasses the entire original literature on Finkelstein-Seidlmayer vasculitis published after the original description and is attainable on request. The possible existence of an infectious or a vaccine precursor was addressed in 447 cases. Most cases were preceded by an infection (N = 384; 86%), by a vaccination (N = 20; 4.4%), or both an infection and a vaccination (N = 17; 3.8%). No precursor was reported in the remaining cases (N = 26; 5.8%). Two distinct infections preceded the onset of the vasculitis in 11 of the 381 cases with infection-associated Finkelstein-Seidlmayer vasculitis. The following infectious precursors were reported: upper respiratory tract infection (N = 292); acute gastroenteritis (N = 40); a benign febrile infection (N = 36); lower respiratory tract infection (N = 22); further infections (N = 8). The temporal relationship between the infectious precursor and the onset of the skin eruption was detailed in 336 cases: 54 cases developed before resolution and 282 after resolution of the infection. In conclusion, most cases of Finkelstein-Seidlmayer vasculitis are preceded by an infection. In a minority of cases, this skin vasculitis develops before resolution of the infection. In most cases, however, this vasculitis develops after resolution of the infection. More rarely, this vasculitis is preceded by a vaccination.

Indexed as

ExanthemaVaccinesVasculitis, Leukocytoclastic, CutaneousChildChild, PreschoolEdemaHemorrhageHumansInfantSkinVaccinesAcute hemorrhagic edema of young childrenCockade purpura with edemaFinkelstein-Seidlmayer vasculitisInfectionPrecursorSmall-vessel leukocytoclastic vasculitisVaccination

Identifiers

PMID35553000
PMCPMC9096064
OpenAlexW4280511093

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.