ReviewEndocrine reviews2022
The Role of Iodine for Thyroid Function in Lactating Women and Infants.
Review in Endocrine reviews, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 57 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
57 citing papers in PubMed, 3 syntheses or guidelines pooled it, 108 citations in OpenAlex.
- Dairy Intake and Iodine Status in Pregnant and Lactating Women: A Systematic Review and Meta-Analysis.Nutrients · 2025Pooled it
- Do Postpartum Maternal Iodine Status or Supplementation Affect Thyroid Function After Delivery? A Systematic Review and Meta-Analysis.Biological trace element research · 2024Pooled it
- The Role of Selected Trace Elements in Oxidoreductive Homeostasis in Patients with Thyroid Diseases.International journal of molecular sciences · 2023Pooled it
- Iodine Status of Mother-Infant Dyads from Montréal, Canada: Secondary Analyses of a Vitamin D Supplementation Trial in Breastfed Infants.The Journal of nutrition · 2022Trial
- Correlation Between Salivary and Urinary Iodine Indicators in Lactating Women: A Cross-Sectional Study.Biological trace element research · 2026Article
- Urinary Iodine and Maternal Thyroid Hormones Across Pregnancy Trimesters: a Stratified and Nonlinear Analysis from 2020-2024.Biological trace element research · 2026Article
- Effects of per- and polyfluoroalkyl substances on maternal thyroid function: a stratified analysis by maternal iodine status and thyroid autoantibody status.BMC pregnancy and childbirth · 2026Article
- The Impact of the COVID-19 Pandemic on Iodine Nutrition Status of Pregnant Women and Infants/Toddlers: Repeated Cross-Sectional Studies in Zhengzhou, China.Biological trace element research · 2026Article
- Iodine Supplementation Before, During and After Pregnancy.Geburtshilfe und Frauenheilkunde · 2026Article
- Influence of Heat Treatment Prior to Fortification on Goitrogenic Compounds, Iodine Stability and Antioxidant Activity in Cauliflower.Foods (Basel, Switzerland) · 2026Article
- Review
- Could iodine be the missing micronutrient in breast cancer development?Frontiers in oncology · 2026Article
- Iodine concentrations in human milk after maternal high therapeutic potassium iodide dosing during breastfeeding: a contribution from the ConcePTION project.Therapeutic advances in endocrinology and metabolism · 2026Article
- Knowledge, Utilization Practices, and Adequacy of Iodized Salt Among Pregnant Women in Awash Sebat Administrative City, Afar Region, Ethiopia: A Bayesian Logistic Regression Analysis.Journal of nutrition and metabolism · 2026Article
- Some subgroups of U.S. childbearing women are still at risk of iodine deficiency in the 21 st century: a cross-sectional analysis of NHANES 2001-2020.BMC pregnancy and childbirth · 2025Article
- [Importance and supply of micronutrients in infants, children and adolescents].Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz · 2025Article
- Associations of urinary iodine concentration (UIC) with Metabolic Dysfunction-associated Steatotic Liver Disease (MASLD) among non-diabetic population: analysis of the NHANES 2017-2020.BMC gastroenterology · 2025Article
- Reference Values for Minerals in Human Milk: the Mothers, Infants and Lactation Quality (MILQ) Study.Advances in nutrition (Bethesda, Md.) · 2025Article
- Two-Dose Crossover Iodine Balance Study: Iodine Requirements for Toddlers in China.Biological trace element research · 2025Article
- [Iodine status of the population in the WHO European Region (an abridged translation of selected sections of the WHO European report)].Problemy endokrinologii · 2025Review
Corrections and comments
- Erratum issued
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Iodine is a micronutrient needed for the production of thyroid hormones, which regulate metabolism, growth, and development. Iodine deficiency or excess may alter the thyroid hormone synthesis. The potential effects on infant development depend on the degree, timing, and duration of exposure. The iodine requirement is particularly high during infancy because of elevated thyroid hormone turnover. Breastfed infants rely on iodine provided by human milk, but the iodine concentration in breast milk is determined by the maternal iodine intake. Diets in many countries cannot provide sufficient iodine, and deficiency is prevented by iodine fortification of salt. However, the coverage of iodized salt varies between countries. Epidemiological data suggest large differences in the iodine intake in lactating women, infants, and toddlers worldwide, ranging from deficient to excessive intake. In this review, we provide an overview of the current knowledge and recent advances in the understanding of iodine nutrition and its association with thyroid function in lactating women, infants, and toddlers. We discuss risk factors for iodine malnutrition and the impact of targeted intervention strategies on these vulnerable population groups. We highlight the importance of appropriate definitions of optimal iodine nutrition and the need for more data assessing the risk of mild iodine deficiency for thyroid disorders during the first 2 years in life.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.