Evidence map›Paper›PMID 35552393›Full record

ArticleDevelopment (Cambridge, England)2022

Zebrafish behavior as a gateway to nervous system assembly and plasticity.

Jessica C Nelson, Michael Granato

Abstract read
In one paragraph

Article in Development (Cambridge, England), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Jessica C NelsonDepartment of Cell and Developmental Biology, University of Colorado, Anschutz Medical Campus, Aurora, CO 80045, USA.ORCID 0000-0001-7528-4245
Michael GranatoDepartment of Cell and Developmental Biology, University of Pennsylvania, Perelman School of Medicine, 421 Curie Blvd, Philadelphia, PA 19104, USA.ORCID 0000-0003-3878-9468

Funding

Cellular and molecular analysis of startle modulationR01NS118921 · NINDS · UNIVERSITY OF PENNSYLVANIA · PI GRANATO, MICHAEL · 2021 to 2025
$2.6M
Understanding how post-translational palmitoylation influences in vivo molecular and circuit dynamics during learningR00NS111736 · NINDS · UNIVERSITY OF COLORADO DENVER · PI NELSON, JESSICA C · 2022 to 2024
$722k
Understanding how post-translational palmitoylation influences in vivo molecular and circuit dynamics during learningK99NS111736 · NINDS · UNIVERSITY OF PENNSYLVANIA · PI NELSON, JESSICA C · 2019 to 2020
$197k
NINDS NIH HHS K99 NS111736NINDS NIH HHS R00 NS111736NINDS NIH HHS R01 NS118921
6 · The paper itself

Abstract

Nervous system assembly relies on a diversity of cellular processes ranging from dramatic tissue reorganization to local, subcellular changes all driven by precise molecular programs. Combined, these processes culminate in an animal's ability to plan and execute behaviors. Animal behavior can, therefore, serve as a functional readout of nervous system development. Benefitting from an expansive and growing set of molecular and imaging tools paired with an ever-growing number of assays of diverse behaviors, the zebrafish system has emerged as an outstanding platform at the intersection of nervous system assembly, plasticity and behavior. Here, we summarize recent advancements in the field, including how developing neural circuits are refined to shape complex behaviors and plasticity.

Indexed as

Nervous SystemZebrafishAnimalsBehavior, AnimalNeuronal PlasticityBehaviorNervous systemPhenotypePlasticityZebrafish

Identifiers

PMID35552393
PMCPMC9148562

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.