Evidence map›Paper›PMID 35552308›Full record

ReviewCurrent opinion in urology2022

The role of prostate-specific membrane antigen PET/computed tomography in the management of prostate cancer patients: could we ask for more?

Riccardo Mei, Andrea Farolfi, Joshua James Morigi, Stefano Fanti

Open access · hybridAbstract readReview
In one paragraph

Review in Current opinion in urology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Japanese journal of radiology · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 4 institutions in 2 countries.

Riccardo MeiNuclear Medicine, IRCCS, Azienda Ospedaliero-Universitaria di Bologna.
Andrea FarolfiNuclear Medicine, IRCCS, Azienda Ospedaliero-Universitaria di Bologna.
Joshua James MorigiPET/CT Unit, Department of Medical Imaging, Royal Darwin Hospital, Darwin, Australia.
Stefano FantiNuclear Medicine, IRCCS, Azienda Ospedaliero-Universitaria di Bologna.
Azienda USL di Bologna · ITIstituti di Ricovero e Cura a Carattere Scientifico · ITRoyal Darwin Hospital · AUUniversity of Bologna · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purpose of reviewThanks to the development of novel PSMA-based peptides, molecular imaging, such as PET/CT paired with theranostic-based approaches have recently been proposed for treatment of prostate cancer. Patient selection, however, remains challenging because of the absence of strong prospective data to interpret and translate imaging scans into effective and well tolerated treatment regimens. RECENT

findingsIn this review, we discuss the latest findings in PSMA imaging in prostate cancer patients. Particularly, we go into detail into the impact of PSMA imaging on the treatment management in primary staging, biochemical recurrence and in advanced prostate cancer. SUMMARY: For primary prostate cancer staging, PSMA PET/CT seems crucial for primary therapy assessment, being able in some cases to detect lesions outside the surgical template, thus permitting a change in management. Moreover, N+ condition at PSMA has been correlated with a worse biochemical recurrence-free and therapy-free survival. The early detection of PSMA-positive findings in recurrent prostate cancer is associated with a better time to relapse survival. Similarly, for advanced prostate cancer patients, accurate restaging with PSMA imaging is gaining importance for early prediction of response to systemic therapies and to assure the best outcome possible. With regards to theranostics, appropriate selection of patients eligible for 177Lu-PSMA requires PSMA imaging, whereas the role of added FDG-PET for discriminating those with PSMA/FDG discordance needs to be further evaluated.

Indexed as

Positron Emission Tomography Computed TomographyProstatic NeoplasmsFluorodeoxyglucose F18HumansMaleNeoplasm Recurrence, LocalProspective StudiesProstateFluorodeoxyglucose F18

Identifiers

PMID35552308
PMCPMC10810346
OpenAlexW4280514770

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.