ArticleAnnals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology2022
The association between duration of breastfeeding and childhood asthma outcomes.
Article in Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed, 28 citations in OpenAlex.
- Association of breastfeeding with caregiver-reported physician-diagnosed allergies in children: the Japan Environment and Children's Study.BMC pediatrics · 2026Article
- The role of the early-life gut microbiome in childhood asthma.Gut microbes · 2025Review
- Article
- Article
- Association of prenatal vitamin E levels with child asthma and wheeze.Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology · 2024Article
- Maternal stressful life events during pregnancy and childhood asthma and wheeze.Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology · 2024Article
- Association of Prenatal Maternal and Infant Vitamin D Supplementation with Offspring Asthma.Annals of the American Thoracic Society · 2024Article
- Impact analysis of infant antibiotic exposure on the burden of asthma: a simulation modeling study.Frontiers in allergy · 2024Article
- [Relationship between atherogenic index of plasma and childhood asthma].Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2023Article
- Role of Air Pollution in the Development of Asthma Among Children with a History of Bronchiolitis in Infancy.Epidemiology (Cambridge, Mass.) · 2023Article
- Relation of Maternal Pre-Pregnancy Factors and Childhood Asthma: A Cross-Sectional Survey in Pre-School Children Aged 2-5 Years Old.Medicina (Kaunas, Lithuania) · 2023Article
- Association between maternal occupational exposure to cleaning chemicals during pregnancy and childhood wheeze and asthma.Frontiers in epidemiology · 2023Article
- Association of Severe Bronchiolitis during Infancy with Childhood Asthma Development: An Analysis of the ECHO Consortium.Biomedicines · 2022Article
- Association between History of Prolonged Exclusive Breast-Feeding and the Lung Function Indices in Childhood.Children (Basel, Switzerland) · 2022Article
- Cohort profile: the ECHO prenatal and early childhood pathways to health consortium (ECHO-PATHWAYS).BMJ open · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
16 authors at 8 institutions in 1 country.
Funding
Abstract
backgroundPostnatal exposures, including breastfeeding, may influence asthma development.
objectiveTo investigate the association between breastfeeding duration and child asthma.
methodsWe studied 2021 mother-child dyads in the ECHO PATHWAYS consortium of prospective pregnancy cohorts (GAPPS, CANDLE, TIDES). Women reported the duration of any and exclusive breastfeeding and child asthma outcomes during follow-up at child age 4 to 6 years. Outcomes included current wheeze (previous 12 months), ever asthma, current asthma (having ≥2 of current wheeze, ever asthma, medication use in past 12-24 months), and strict current asthma (ever asthma with either or both current wheeze and medication use in past 12-24 months). We used multivariable logistic regression to assess associations (odds ratios and 95% confidence intervals) between breastfeeding and asthma outcomes adjusting for potential confounders. We assessed effect modification by mode of delivery, infant sex, and maternal asthma.
resultsAmong women, 33%, 13%, 9%, and 45% reported 0 to less than 2, 2 to 4, 5 to 6, and more than 6 months of any breastfeeding, respectively. The duration of any breastfeeding had a protective linear trend with ever asthma but no other outcomes. There was a duration-dependent protective association of exclusive breastfeeding and child asthma outcomes (eg, current asthma adjusted odds ratio [95% confidence interval], 0.64 [0.41-1.02], 0.61 [0.38-0.98], and 0.52 (0.31-0.87) for 2to 4 months, 5 to 6 months, and more than 6 months, respectively, compared with <2 months). For exclusive breastfeeding, protective associations were stronger in dyads with children born by vaginal vs cesarean delivery although interactions did not reach statistical significance (P
conclusionLonger duration of exclusive breastfeeding had a protective association with child asthma.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.