Evidence map›Paper›PMID 35551996›Full record

ArticleAnnals of epidemiology2022

Home-to-hospital distance and outcomes among community-acquired sepsis hospitalizations.

Joshua F Detelich, Nang Thu Kyaw, Suzanne E Judd, Aleena Bennett, Henry E Wang, Michael R Kramer, Lance A Waller, Greg S Martin, Jordan A Kempker

Open access · greenAbstract read
In one paragraph

Article in Annals of epidemiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.5field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 3 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 1 country.

Joshua F DetelichDivision of Pulmonary, Allergy, Critical Care and Sleep Medicine, Emory University School of Medicine, Atlanta, GA. Electronic address: jdeteli@emory.edu.
Nang Thu KyawDivision of Epidemiology and Biostatistics, School of Public Health, Georgia State University, Atlanta, GA.
Suzanne E JuddDepartment of Biostatistics, University of Alabama at Birmingham, Birmingham, AL.
Aleena BennettDepartment of Biostatistics, University of Alabama at Birmingham, Birmingham, AL.
Henry E WangDepartment of Emergency Medicine, The Ohio State University, Columbus, OH.
Michael R KramerDepartment of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, GA.
Lance A WallerDepartment of Biostatistics and Bioinformatics, Rollins School of Public Health, Emory University, Atlanta, GA.
Greg S MartinDivision of Pulmonary, Allergy, Critical Care and Sleep Medicine, Emory University School of Medicine, Atlanta, GA.
Jordan A KempkerDivision of Pulmonary, Allergy, Critical Care and Sleep Medicine, Emory University School of Medicine, Atlanta, GA.
Emory University · USUniversity of Alabama at Birmingham · USEmory Healthcare · USGeorgia State University · USThe Ohio State University · US

Funding

VCID and Stroke in a Bi-racial National CohortU01NS041588 · NINDS · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI CUSHMAN, MARY, HOWARD, GEORGE · 2002 to 2022
$96.0M
Implementing a Maternal health and PRegnancy Outcomes Vision for Everyone (IMPROVE)UL1TR002378 · NCATS · EMORY UNIVERSITY · PI Andres J Garcia, Elizabeth O. Ofili · 2017 to 2026
$92.1M
J: NRSA Training CoreTL1TR002382 · NCATS · EMORY UNIVERSITY · PI HENRY M BLUMBERG, Vasiliki Michopoulos · 2017 to 2026
$8.5M
The Emory Training Program in Lung HealthT32HL116271 · NHLBI · EMORY UNIVERSITY · PI BROWN, LOU ANN S, GUIDOT, DAVID MARSHALL · 2013 to 2022
$4.2M
A Geographic Approach to Determining the Preventable Causes of US Sepsis MortalityK08HS025240 · AHRQ · EMORY UNIVERSITY · PI KEMPKER, JORDAN ANTHONY · 2018 to 2020
$451k
AHRQ HHS K08 HS025240NCATS NIH HHS TL1 TR002382NCATS NIH HHS UL1 TR002378NHLBI NIH HHS T32 HL116271NINDS NIH HHS U01 NS041588
6 · The paper itself

Abstract

purposeTo examine the hypothesis that longer distance from home-to-hospital is associated with worse outcomes among hospitalizations for community-acquired sepsis.

methodsA secondary analysis of data from the REasons for Geographic and Racial Differences in Stroke (REGARDS) prospective cohort of 30,239 white and Black US adults greater than or equal to 45 years old was conducted. Self-reported hospitalizations for serious infection between 2003 and 2012 fulfilling 2/4 systemic inflammatory response syndrome criteria were included. Estimated driving distance was derived from geocoded data and evaluated continuously and as quartiles of very close, close, far, very far (<3.1, 3.1-5.8, 5.9-11.5, and >11.5 miles respectively). The primary outcome was 30-day mortality while the secondary outcome was sequential organ failure assessment (SOFA) score on arrival.

resultsOf the 912 hospitalizations for community-acquired sepsis had adequate data for analysis. The median (interquartile range) estimated driving distance was 5.8 miles (3.1,11.7), and 54 (5.9%) experienced the primary outcome. Compared to living very close, participants living very far had a mortality odds ratio of 1.30 (95% CI 0.64,2.62) and presenting SOFA score difference of 0.33 (95% CI -0.03,0.68).

conclusionsAmong a national sample of community-acquired sepsis hospitalizations, there was no significant association between home-to-hospital distance and either 30-day mortality or SOFA score on hospital presentation.

Indexed as

SepsisAdultHospitalizationHospital MortalityHospitalsHumansProspective StudiesRetrospective StudiesDistance to hospitalOutcomesRegardsSepsis

Identifiers

PMID35551996
PMCPMC9629891
OpenAlexW4229367806

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.