ArticleAmerican journal of ophthalmology2022
Rates of Choroidal Microvasculature Dropout and Retinal Nerve Fiber Layer Changes in Glaucoma.
Article in American journal of ophthalmology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
8 citing papers in PubMed.
- Progression in Preperimetric Glaucoma Eyes With and Without Microvasculature Dropout.American journal of ophthalmology · 2026Article
- Ocular Blood Flow in Eyes with Myopia and Glaucoma: From Pathophysiology to Clinical Implications.Journal of clinical medicine · 2026Review
- Optic Disc Structural Progression in Glaucoma Suspect Eyes With Microvascular Dropout.American journal of ophthalmology · 2026Article
- Enlargement of microvascular dropout toward the disc-fovea axis indicates new central visual field defect in glaucoma.Scientific reports · 2025Article
- Reduction of Optic Disc Microvasculature and Retinal Nerve Fiber Layer Thinning in Patients With Glaucoma.American journal of ophthalmology · 2024Article
- Parapapillary choroidal microvasculature dropout in eyes with primary open-angle glaucoma.Scientific reports · 2023Article
- Impact of smoking on choroidal microvasculature dropout in glaucoma: a cross-sectional study.BMJ open ophthalmology · 2023Article
- Optical Coherence Tomography and Optical Coherence Tomography Angiography: Essential Tools for Detecting Glaucoma and Disease Progression.Frontiers in ophthalmology · 2023Article
Corrections and comments
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Authors and funding
9 authors.
Funding
Abstract
purposeTo evaluate the association between rates of choroidal microvasculature dropout (MvD) change and rates of circumpapillary retinal nerve fiber layer (cpRNFL) loss in primary open-angle glaucoma (POAG) eyes.
designCohort study from clinical trial data.
methodsA total of 91 eyes of 68 POAG patients with and without localized MvD at baseline with at least 4 visits and 2 years of follow-up with optical coherence tomography angiography (OCT-A) and OCT scans were included. Area and angular circumference of MvD were evaluated on OCT-A en face and B-scan choroidal vessel density images during the follow-up period. Joint longitudinal mixed effects models were used to estimate the rates of change in MvD area or angular circumference and RNFL thickness. Univariable and multivariable regressions were completed to identify the factors contributing to cpRNFL thinning.
resultsMvD was identified in 53 eyes (58.2%) at baseline. Seventeen eyes (18.6%) that did not show MvD at baseline developed it over the follow-up period. Over a mean follow-up of 4.0 years, the mean rates of change in MvD area and angular circumference (95% CI) were 0.05 (0.04, 0.06) mm
conclusionsRates of MvD area and angular circumference change over time were associated with concurrent rates of cpRNFL loss in POAG eyes.
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