ArticleBiology of sex differences2022
Visceral adiposity index and sex differences in relation to peripheral artery disease in normal-weight adults with hypertension.
Article in Biology of sex differences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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15 citing papers in PubMed, 18 citations in OpenAlex.
- Triglyceride-Glucose-Related Indexes as Risk Factors for Vision-Threatening Ocular Diseases: A Prospective UK Biobank Study.Investigative ophthalmology & visual science · 2026Article
- Comparative predictive value of anthropometric indexes for hypertension: a 15-year prospective cohort study.Internal and emergency medicine · 2026Article
- Association between new metabolic indices and atrial fibrillation in elderly hypertensive patients in China.BMC geriatrics · 2026Article
- The metabolic score for visceral fat and risk of peripheral arterial disease in hypertension patients: a prospective cohort study.Frontiers in endocrinology · 2026Article
- Impact of remnant cholesterol on arterial stiffness and mediating role of systolic blood pressure in chinese hypertensive adults.BMC public health · 2025Article
- The Visceral Adiposity Index and Its Usefulness in the Prediction of Cardiometabolic Disorders.Nutrients · 2025Review
- Perirenal adipose tissue accumulation mediates the adverse impact of the atherogenic index of plasma on lower extremity peripheral arterial disease.Scientific reports · 2025Article
- Exploring Visceral Fat as a Screening Marker for Cardiometabolic Risk in Children and Adolescents.Children (Basel, Switzerland) · 2025Article
- The association of obesity and lipid-related indicators with all-cause and cardiovascular mortality risks in patients with diabetes or prediabetes: a cross-sectional study based on machine learning algorithms.Frontiers in endocrinology · 2025Article
- Reporting and analysis of sex in vascular surgery research.Journal of vascular surgery · 2024Review
- Association between dietary fiber intake and peripheral artery disease in hypertensive patients.Journal of health, population, and nutrition · 2024Article
- Triglyceride-glucose index change and chronic kidney disease progression in a Chinese hypertensive population.Frontiers in endocrinology · 2024Article
- The associations of obesity phenotypes with the risk of hypertension and its transitions among middle-aged and older Chinese adults.Epidemiology and health · 2023Article
- Association between psoriasis and peripheral artery occlusive disease: a population-based retrospective cohort study.Frontiers in cardiovascular medicine · 2023Article
- Association of Hyper-Triglyceridemic Waist Phenotype and Diabetic Vascular Complication in the Chinese Population.Diabetes, metabolic syndrome and obesity : targets and therapy · 2023Article
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Authors and funding
10 authors at 6 institutions in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
backgroundPrevious studies on the relationship between the visceral adiposity index (VAI) and peripheral arterial disease (PAD) are limited. Therefore, this study explored the relationship between VAI and PAD in normal-weight patients with hypertension.
methodsA total of 6615 normal-weight patients with hypertension were included in the current study. The VAI, a simple index calculated using blood lipid and waist circumference (WC), can be used as a simple biomarker of body fat distribution. The outcome was PAD, which was defined as present when each side's ankle-brachial index (ABI) was ≤ 0.90.
resultsA significant positive association was observed between VAI and PAD prevalence. For per unit increment in LnVAI, the adjusted odds ratios (ORs) of PAD for the total participants and males were 1.55 (95% CI 1.15-2.10) and 2.12 (95% CI 1.46-3.07), respectively. However, the VAI was not associated with PAD in female patients with hypertension (OR 1.28; 95% confidence interval [CI] 0.85-1.95). There was no interaction between sex and VAI (P for interaction = 0.128). Accordingly, in total participants, when VAI was assessed in quartiles and compared with quartile 1 (< 0.84), the PAD prevalence was higher than that of quartiles 2 (0.84 to < 1.36: OR 1.49; 95% CI 0.92-2.44), 3 (1.36 to < 2.25: OR 1.95; 95% CI 1.14-3.32), and 4 (≥ 2.25: OR 1.93; 95% CI 1.04-3.57). There were no significant interactions with the other confounders.
conclusionThis study showed a positive association between VAI and PAD in normal-weight adults with hypertension among men but not among women.
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