Evidence map›Paper›PMID 35551534›Full record

ArticleMolecular biomedicine2022

Characterization of chronic relapsing antibody mediated arthritis in mice with a mutation in Ncf1 causing reduced oxidative burst.

Peibin Liang, Yanpeng Li, Rui Xu, Kutty Selva Nandakumar, Roma Stawikowska, Gregg B Fields, Rikard Holmdahl

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecular biomedicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 3 countries.

Peibin LiangMedical Inflammation Research, Pharmacology School, Southern Medical University, Guangzhou, 510515, China.
Yanpeng LiMedical Inflammation Research, Pharmacology School, Southern Medical University, Guangzhou, 510515, China.
Rui XuMedical Inflammation Research, Pharmacology School, Southern Medical University, Guangzhou, 510515, China.
Kutty Selva NandakumarMedical Inflammation Research, Pharmacology School, Southern Medical University, Guangzhou, 510515, China.
Roma StawikowskaDepartment of Chemistry & Biochemistry and I-HEALTH, Florida Atlantic University, Jupiter, FL, USA.
Gregg B FieldsDepartment of Chemistry & Biochemistry and I-HEALTH, Florida Atlantic University, Jupiter, FL, USA.
Rikard HolmdahlMedical Inflammation Research, Pharmacology School, Southern Medical University, Guangzhou, 510515, China. rikard.holmdahl@ki.se.ORCID http://orcid.org/0000-0002-4969-2576
Southern Medical University · CNFlorida Atlantic University · USKarolinska Institutet · SE

Funding

Autoantibody modulation of cartilage turnover in rheumatoid arthritisR15AI154248 · NIAID · FLORIDA ATLANTIC UNIVERSITY · PI FIELDS, GREGG B · 2021 to 2021
$429k
Guangdong Province 201001Y04675344NIAID NIH HHS R15 AI154248School of Pharmaceutical Sciences, Southern Medical University C1051017School of Pharmaceutical Sciences, Southern Medical University G619310007
6 · The paper itself

Abstract

Rheumatoid arthritis (RA) is a chronic autoimmune disorder affecting joints with a hallmark of autoantibody production. Mannan-enhanced collagen type II (COL2) antibody induced arthritis (mCAIA) in neutrophil cytosolic factor 1(Ncf1) mutation mouse is a chronic disease model imitating RA in mice. In this study, we characterize the chronic phase of mCAIA in Ncf1 mutated (BQ.Ncf1

Indexed as

Anti-COL2 antibodyChronic phaseCollagen type II induced arthritisNeutrophil cytosolic factor 1Rheumatoid arthritis

Identifiers

PMID35551534
PMCPMC9098740
OpenAlexW4280501119

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.