Evidence map›Paper›PMID 35551272›Full record

ArticlePLoS neglected tropical diseases2022

A mechanistic model of snakebite as a zoonosis: Envenoming incidence is driven by snake ecology, socioeconomics and its impacts on snakes.

Gerardo Martín, Joseph J Erinjery, Dileepa Ediriweera, H Janaka de Silva, David G Lalloo, Takuya Iwamura, Kris A Murray

Open access · goldAbstract read
In one paragraph

Article in PLoS neglected tropical diseases, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
3.4field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 18 citations in OpenAlex.

  1. Snakebite-Associated Infections: A Systematic Review and Meta-Analysis.The American journal of tropical medicine and hygiene · 2024
    Pooled it
  2. Article
  3. Review
  4. Article
  5. Article
  6. The incidence of snakebite in South Africa and the challenges associated with lack of reporting.Transactions of the Royal Society of Tropical Medicine and Hygiene · 2025
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Identification of Risk Areas forAnimals : an open access journal from MDPI · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 6 institutions in 7 countries.

Gerardo MartínMRC Centre for Global Infectious Disease Analysis, Imperial College London, London, United Kingdom.ORCID 0000-0003-3608-5328
Joseph J ErinjerySchool of Zoology, Department of Life Sciences, Tel Aviv University, Tel Aviv, Israel.ORCID 0000-0002-5690-838X
Dileepa EdiriweeraFaculty of Medicine, University of Kelaniya, Ragama, Sri Lanka.ORCID 0000-0001-5679-2893
H Janaka de SilvaFaculty of Medicine, University of Kelaniya, Ragama, Sri Lanka.
David G LallooLiverpool School of Tropical Medicine, Liverpool, United Kingdom.
Takuya IwamuraDepartment of Forest Ecosystems and Society, College of Forestry, Oregon State University, Corvallis, Oregon, United States of America.ORCID 0000-0002-3740-7758
Kris A MurrayMRC Centre for Global Infectious Disease Analysis, Imperial College London, London, United Kingdom.ORCID 0000-0002-8382-0674
University of Kelaniya · LKImperial College London · GBLiverpool School of Tropical Medicine · GBMRC Unit the Gambia · GMOregon State University · USTel Aviv University · IL

Funding

Medical Research Council MP/P024513/1Medical Research Council MR/P024513/1Medical Research Council MR/R015600/1
6 · The paper itself

Abstract

Snakebite is the only WHO-listed, not infectious neglected tropical disease (NTD), although its eco-epidemiology is similar to that of zoonotic infections: envenoming occurs after a vertebrate host contacts a human. Accordingly, snakebite risk represents the interaction between snake and human factors, but their quantification has been limited by data availability. Models of infectious disease transmission are instrumental for the mitigation of NTDs and zoonoses. Here, we represented snake-human interactions with disease transmission models to approximate geospatial estimates of snakebite incidence in Sri Lanka, a global hotspot. Snakebites and envenomings are described by the product of snake and human abundance, mirroring directly transmitted zoonoses. We found that human-snake contact rates vary according to land cover (surrogate of occupation and socioeconomic status), the impacts of humans and climate on snake abundance, and by snake species. Our findings show that modelling snakebite as zoonosis provides a mechanistic eco-epidemiological basis to understand snakebites, and the possible implications of global environmental and demographic change for the burden of snakebite.

Indexed as

Snake BitesAnimalsAntiveninsHumansIncidenceSnakesSocioeconomic FactorsZoonosesAntivenins

Identifiers

PMID35551272
PMCPMC9129040
OpenAlexW4280511407

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.