Evidence map›Paper›PMID 35551208›Full record

ArticleScientific reports2022

Cognitive and hippocampal changes weeks and years after memory training.

Anne Cecilie Sjøli Bråthen, Øystein Sørensen, Ann-Marie G de Lange, Athanasia M Mowinckel, Anders M Fjell, Kristine B Walhovd

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 25 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Anne Cecilie Sjøli BråthenDepartment of Psychology, Center for Lifespan Changes in Brain and Cognition, University of Oslo, 0317, Oslo, Norway. a.c.s.brathen@psykologi.uio.no.
Øystein SørensenDepartment of Psychology, Center for Lifespan Changes in Brain and Cognition, University of Oslo, 0317, Oslo, Norway.
Ann-Marie G de LangeDepartment of Psychology, Center for Lifespan Changes in Brain and Cognition, University of Oslo, 0317, Oslo, Norway.
Athanasia M MowinckelDepartment of Psychology, Center for Lifespan Changes in Brain and Cognition, University of Oslo, 0317, Oslo, Norway.
Anders M FjellDepartment of Psychology, Center for Lifespan Changes in Brain and Cognition, University of Oslo, 0317, Oslo, Norway.
Kristine B WalhovdDepartment of Psychology, Center for Lifespan Changes in Brain and Cognition, University of Oslo, 0317, Oslo, Norway.
University of Oslo · NOOslo University Hospital · NO

Funding

European Research Council 771355European Research Council ERC grant agreement 313440 to K.B.W
6 · The paper itself

Abstract

While immediate effects of memory-training are widely reported in young and older adults, less is known regarding training-dependent hippocampal plasticity across multiple intervention phases, and long-term maintenance of such. Here, 157 healthy young and older adults underwent a training-intervention including two 10 weeks periods of episodic-memory training, separated by two 2 weeks periods of no training. Both age groups showed improvements on a criterion task, which prevailed after 3 years. When compared to the reference condition of no training, relative increases in hippocampal volume were observed after the training across age groups, which were maintained after 10 weeks periods of no training. However, there was age-group dependent temporal variation with respect to timing of effects. Hippocampal volume of the training group did not differ from that of a passive control-group 3 years after the intervention. The young showed an immediate near-transfer effect on a word-association task. We show that training-gains on memory performance can prevail for at least 3 years. Memory training can induce increases in hippocampal volume immediately after the intervention and after months. Episodic-memory training can produce transfer effects to a non-trained memory task in young adults. However, maintained effects on hippocampal volume beyond 10 weeks are uncertain, and likely require continuous training.

Indexed as

Memory, EpisodicMemory, Short-TermAgedChild, PreschoolCognitionHippocampusHumansInfantLearningYoung Adult

Identifiers

PMID35551208
PMCPMC9098907
OpenAlexW4280499806

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.