Evidence map›Paper›PMID 35551191›Full record

ArticleNature communications2022

Structural basis of ion - substrate coupling in the Na

David B Sauer, Jennifer J Marden, Joseph C Sudar, Jinmei Song, Christopher Mulligan, Da-Neng Wang

Open access · goldAbstract read
In one paragraph

Article in Nature communications, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 29 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Elevator mechanism dynamics in a sodium-coupled dicarboxylate transporter.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  7. Article
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  11. Cryo-EM structures reveal the HLife science alliance · 2025
    Article
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  15. Article
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  18. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

David B SauerDepartment of Cell Biology, New York University School of Medicine, New York, NY, 10016, USA.
Jennifer J MardenDepartment of Cell Biology, New York University School of Medicine, New York, NY, 10016, USA.
Joseph C SudarSkirball Institute of Biomolecular Medicine, New York University School of Medicine, New York, NY, 10016, USA.ORCID 0000-0002-0112-1934
Jinmei SongDepartment of Cell Biology, New York University School of Medicine, New York, NY, 10016, USA.
Christopher MulliganSchool of Biosciences, University of Kent, Canterbury, Kent, UK. c.mulligan@kent.ac.uk.ORCID 0000-0001-5157-4651
Da-Neng WangDepartment of Cell Biology, New York University School of Medicine, New York, NY, 10016, USA. da-neng.wang@med.nyu.edu.ORCID 0000-0002-6496-4699
New York University · USUniversity of Kent · GBUniversity of Oxford · GB

Funding

Transport Cycle and Inhibition of Human Na+-dicarboxylate Cotransporter NaDC3R01NS108151 · NINDS · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI DANENG WANG · 2018 to 2026
$4.1M
Structural and Mechanistic Characterization of Neurotransmitter Reuptake InhibitiR01MH083840 · NIMH · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI WANG, DANENG · 2008 to 2012
$2.2M
Structural basis of the Ragulator-Rag GTPase complex as a platform for mTOR activation on the lysosomal surfaceR01GM121994 · NIGMS · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI WANG, DANENG · 2017 to 2020
$1.5M
Structural and mechanistic studies of INDY proteinsR01DK099023 · NIDDK · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI WANG, DANENG · 2013 to 2016
$1.5M
Structural Basis of Tetracycline Resistance by Efflux Pump TetL.R01GM093825 · NIGMS · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI WANG, DANENG · 2010 to 2014
$1.4M
Biotechnology and Biological Sciences Research Council BB/V007424/1NIDDK NIH HHS R01 DK099023NIGMS NIH HHS R01 GM093825NIGMS NIH HHS R01 GM121994NIMH NIH HHS R01 MH083840NINDS NIH HHS R01 NS108151Wellcome TrustWellcome Trust 210121/Z/18/Z
6 · The paper itself

Abstract

The Na

Indexed as

Dicarboxylic Acid TransportersVibrio choleraeBinding SitesSodiumSuccinic AcidDicarboxylic Acid TransportersSodiumSuccinic Acid

Identifiers

PMID35551191
PMCPMC9098524
OpenAlexW4280509316

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.