ArticleNature communications2022
Sensory adaptation mediates efficient and unambiguous encoding of natural stimuli by vestibular thalamocortical pathways.
Article in Nature communications, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed.
- Distributed burst firing mediates optimized cortical encoding of natural self-motion.Science advances · 2026Article
- Toward a neuroergonomic understanding of spatial disorientation.Frontiers in physiology · 2026Review
- In vivo neural activity of electrosensory pyramidal cells: Biophysical characterization and phenomenological modeling.PLoS computational biology · 2025Article
- Noisy galvanic vestibular stimulation induces stochastic resonance in vestibular perceptual thresholds assessed efficiently using confidence reports.Experimental brain research · 2024Article
- Exploring physiological stress response evoked by passive translational acceleration in healthy adults: a pilot study utilizing electrodermal activity and heart rate variability measurements.Scientific reports · 2024Article
- Neural populations within macaque early vestibular pathways are adapted to encode natural self-motion.PLoS biology · 2024Article
- Temporal and spatial properties of vestibular signals for perception of self-motion.Frontiers in neurology · 2023Review
- Head-centric computing for vestibular stimulation under head-free conditions.Frontiers in bioengineering and biotechnology · 2023Article
- Neural substrates of perception in the vestibular thalamus during natural self-motion: A review.Current research in neurobiology · 2023Review
- Sensory adaptation mediates efficient and unambiguous encoding of natural stimuli by vestibular thalamocortical pathways.Nature communications · 2022Article
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6 authors.
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Abstract
Sensory systems must continuously adapt to optimally encode stimuli encountered within the natural environment. The prevailing view is that such optimal coding comes at the cost of increased ambiguity, yet to date, prior studies have focused on artificial stimuli. Accordingly, here we investigated whether such a trade-off between optimality and ambiguity exists in the encoding of natural stimuli in the vestibular system. We recorded vestibular nuclei and their target vestibular thalamocortical neurons during naturalistic and artificial self-motion stimulation. Surprisingly, we found no trade-off between optimality and ambiguity. Using computational methods, we demonstrate that thalamocortical neural adaptation in the form of contrast gain control actually reduces coding ambiguity without compromising the optimality of coding under naturalistic but not artificial stimulation. Thus, taken together, our results challenge the common wisdom that adaptation leads to ambiguity and instead suggest an essential role in underlying unambiguous optimized encoding of natural stimuli.
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