Evidence map›Paper›PMID 35550918›Full record

ArticleClinics in dermatology

A definite case of Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) induced by administration of the Pfizer/BioNTech BNT162b2 vaccine for SARS-CoV2.

Jan Walter Schroeder, Chiara Gamba, Andrea Toniato, COVID-19 Study Group, Franco Rongioletti

Open access · greenAbstract read
In one paragraph

Article in Clinics in dermatology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.7field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Jan Walter SchroederFrom the Unit of Allergology and Immunology, ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy, allergologia@ospedaleniguarda.it.
Chiara GambaFrom the Unit of Allergology and Immunology, ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy, allergologia@ospedaleniguarda.it.
Andrea ToniatoFrom the Unit of Allergology and Immunology, ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy, allergologia@ospedaleniguarda.it. Electronic address: andrea.toniato@ospedaleniguarda.it.
COVID-19 Study GroupFrom the Unit of Allergology and Immunology, ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy, allergologia@ospedaleniguarda.it; From the Unit of Pathological Anatomy and Cytogenetics, ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy, anatpat@ospedaleniguarda.it.
Franco RongiolettiFrom the Dermatology Clinic, Vita-Salute S. Raffaele University, Milan, Italy.
Azienda Socio Sanitaria Territoriale Grande Ospedale Metropolitano Niguarda · ITVita-Salute San Raffaele University · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

At the end of December 2020, the anti-SARS-CoV2 vaccination campaign began in Italy. As the number of vaccinated subjects in the general population has increased, several adverse reactions have been observed and reported. Severe cutaneous adverse reactions (SCARs) induced by drugs or vaccines are rare but distinguished by high mortality and include DRESS syndrome or drug induced hypersensitivity syndrome (DiHS), a condition characterized by skin rash, eosinophilia, fever, lymphadenopathy, and involvement of one or more internal organs. Here we present a definite case of DRESS that occured following the administration of Pfizer/BioNTech COVID 19 vaccine. He required hospitalization and was managed with supportive care, antihistamines, and intravenous steroid.

Indexed as

COVID-19COVID-19 VaccinesDrug Hypersensitivity SyndromeEosinophiliaBNT162 VaccineHumansMaleSARS-CoV-2VaccinesBNT162 VaccineCOVID-19 VaccinesVaccines

Identifiers

PMID35550918
PMCPMC9085440
OpenAlexW4229450197

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.