Evidence map›Paper›PMID 35550785›Full record

ReviewSeminars in fetal & neonatal medicine2022

Infection prevention for extremely low birth weight infants in the NICU.

Noa Fleiss, Samiksha Tarun, Richard A Polin

Abstract readReview
In one paragraph

Review in Seminars in fetal & neonatal medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed.

  1. Trial
  2. Trial
  3. Article
  4. Article
  5. Sepsis in neonates with necrotizing enterocolitis: outcomes and predictive model.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2026
    Article
  6. A machine learning system enables just-in-time risk-stratified sepsis evaluations in the neonatal intensive care unit.Journal of perinatology : official journal of the California Perinatal Association · 2026
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. Article
  17. Article
  18. Article
  19. Evolving patterns of healthcare-associated infections in NICU: a five-year retrospective analysis from a tertiary children's hospital in China.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2025
    Article
  20. UnveilingAntibiotics (Basel, Switzerland) · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Noa FleissDepartment of Pediatrics, Yale School of Medicine, New Haven, CT, USA.
Samiksha TarunDepartment of Pediatrics, Columbia University School of Medicine, New York City, NY, USA.
Richard A PolinDepartment of Pediatrics, Columbia University School of Medicine, New York City, NY, USA. Electronic address: Rap32@cumc.columbia.edu.

Funding

Training in Pediatric Infectious DiseasesT32AI007531 · NIAID · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI PRINCE, ALICE S, SAIMAN, LISA · 1998 to 2023
$4.0M
NIAID NIH HHS T32 AI007531
6 · The paper itself

Abstract

Extremely preterm infants are particularly vulnerable to systemic infections secondary to their immature immune defenses, prolonged hospitalizations, delays in enteral feeding, early antibiotic exposure, and need for life-sustaining invasive interventions. There have been several evidence-based practices for infection prevention in this population, such as human milk feedings, utilization of "bundle checklists" and decolonization of pathogenic organisms. Other practices, such as the use of probiotics, human milk-derived fortifiers, and antifungal prophylaxis are more controversial and require further investigation regarding the risks and benefits of such interventions. This chapter examines the susceptibility of the preterm newborn infant to invasive infections and describes several strategies for infection prevention, along with the associated limitations of such practices. It also addresses the various gaps in our understanding of preventing infections in this population, and the need for additional large multi-center randomized controlled trials. Additionally, the role of the SARs-CoV-2 global pandemic and associated strategies for infection prevention in the NICU are discussed.

Indexed as

COVID-19Enterocolitis, NecrotizingHumansInfant, Extremely Low Birth WeightInfant, NewbornInfant, PrematureInfant, Very Low Birth WeightIntensive Care Units, NeonatalSARS-CoV-2AntibioticsExtremely low birth weight infantFungemiaInfection preventionLate onset sepsisNECNeonateNICUProbioticsSARs-CoV-2Very low birth weight infant

Identifiers

PMID35550785
PMCPMC9006400

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.