ArticleAJNR. American journal of neuroradiology2022
ADC Level is Related to DWI Reversal in Patients Undergoing Mechanical Thrombectomy: A Retrospective Cohort Study.
Article in AJNR. American journal of neuroradiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed, 27 citations in OpenAlex.
- Defining the Therapeutic Ceiling of Endovascular Thrombectomy in Large-Core Stroke: Beyond the Limits of ASPECTS.Stroke · 2026Article
- Overestimation of ischemic core on baseline MRI in acute stroke.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2026Article
- Angiographic Success Does Not Fully Reflect Tissue-Level Reperfusion: New Diffusion-Weighted Imaging Lesions After True Complete (TICI 3) Recanalization.Diagnostics (Basel, Switzerland) · 2026Article
- Ischemic core or reversible tissue? Limits of a single ADC threshold in predicting DWI reversal after rapid and successful thrombectomy.European radiology · 2026Article
- Predicting lesion reversal in acute cerebral ischaemia via apparent diffusion coefficient threshold on diffusion-weighted MRI.European radiology · 2026Article
- Revisiting Incomplete Tissue-Level Reperfusion Following Successful Thrombectomy for Acute Ischemic Stroke.Annals of neurology · 2026Review
- Significance of Subtle Diffusion Weighted Imaging Lesion Dynamics: A Comparative Analysis of Methods for Detecting Diffusion Weighted Imaging Lesion Reversal in Endovascular Stroke Treatment.Stroke (Hoboken, N.J.) · 2025Article
- DWI Reversibility in Acute Ischemic Stroke Due to Basilar Artery Occlusion Following Successful Recanalization.Clinical neuroradiology · 2025Observational
- A low apparent diffusion coefficient value is associated with hemorrhagic transformation following endovascular treatment for a large ischemic core.Neuroradiology · 2025Article
- Reversibility of diffuse magnetic resonance imaging following endovascular therapy in acute ischemic stroke: a systematic review and meta-analysis.Quantitative imaging in medicine and surgery · 2025Article
- ADC Threshold Indicating the Ischemic Region for Predicting Efficacy in Thrombectomy.Acta neurochirurgica. Supplement · 2025Article
- The time threshold to reperfusion for DWI reversal in acute ischemic stroke depends on pre-interventional ADC value.Neuroradiology · 2024Article
- Exploring the Limits of Endovascular Therapy for Large Core Patients: Where Do We Need More Data?Stroke · 2024Article
- Evaluation of Large Ischemic Cores to Predict Outcomes of Thrombectomy: A Proposal of a Novel Treatment Phase.Stroke (Hoboken, N.J.) · 2024Article
- Early Metabolic Alteration Predicts Outcome With Middle Cerebral Artery Occlusion Treated by Mechanical Thrombectomy.Stroke (Hoboken, N.J.) · 2023Article
- Predicting Mechanical Thrombectomy Outcome and Time Limit through ADC Value Analysis: A Comprehensive Clinical and Simulation Study Using Machine Learning.Diagnostics (Basel, Switzerland) · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
15 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
background and purposeIn patients with ischemic stroke, DWI lesions can occasionally be reversed by reperfusion therapy. This study aimed to ascertain the relationship between ADC levels and DWI reversal in patients with acute ischemic stroke who underwent recanalization treatment. MATERIALS AND
methodsWe conducted a retrospective cohort study in patients with acute ischemic stroke who underwent endovascular mechanical thrombectomy with successful recanalization between April 2017 and March 2021. DWI reversal was assessed through follow-up MR imaging approximately 24 hours after treatment.
resultsIn total, 118 patients were included. DWI reversal was confirmed in 42 patients. The ADC level in patients with reversal was significantly higher than that in patients without reversal. Eighty-three percent of patients with DWI reversal areas had mean ADC levels of ≥520 × 10
conclusionsIn acute ischemic stroke, the ADC value is independently associated with DWI reversal. Lesions with a mean ADC of ≥520 × 10
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.