Evidence map›Paper›PMID 35550246›Full record

ArticleeLife2022

Conserved structural elements specialize ATAD1 as a membrane protein extraction machine.

Lan Wang, Hannah Toutkoushian, Vladislav Belyy, Claire Y Kokontis, Peter Walter

Open access · goldAbstract read
In one paragraph

Article in eLife, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 23 citations in OpenAlex.

  1. Article
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  7. Review
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  9. Cryo-EM structure of AAA + ATPase thorase reveals novel helical filament formation.Computational and structural biotechnology journal · 2025
    Article
  10. Review
  11. The AAA+ protein Msp1 recognizes substrates by a hydrophobic mismatch.bioRxiv : the preprint server for biology · 2024
    Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Lan Wang *Department of Biochemistry and Biophysics, University of California at San Francisco, San Francisco, United States.ORCID 0000-0002-8931-7201
Hannah Toutkoushian *Department of Biochemistry and Biophysics, University of California at San Francisco, San Francisco, United States.ORCID 0000-0002-7461-2005
Vladislav BelyyDepartment of Biochemistry and Biophysics, University of California at San Francisco, San Francisco, United States.
Claire Y KokontisDepartment of Biochemistry and Biophysics, University of California at San Francisco, San Francisco, United States.ORCID 0000-0001-9397-651X
Peter WalterDepartment of Biochemistry and Biophysics, University of California at San Francisco, San Francisco, United States.ORCID 0000-0002-6849-708X
Howard Hughes Medical Institute · USUniversity of California, San Francisco · US

Funding

MECHANISM OF PROTEIN TRANSLOCATION ACROSS MEMBRANESR01GM032384 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI STROUD, ROBERT M · 1985 to 2023
$7.6M
Howard Hughes Medical InstituteNIGMS NIH HHS R01 GM032384
6 · The paper itself

Abstract

The mitochondrial AAA (

Indexed as

Membrane ProteinsSaccharomyces cerevisiae ProteinsAAA ProteinsAdenosine TriphosphatasesAmino AcidsAmino Acids, AromaticHumansMerozoite Surface Protein 1Saccharomyces cerevisiaeAAA ProteinsAdenosine TriphosphatasesAmino AcidsAmino Acids, AromaticMembrane ProteinsMerozoite Surface Protein 1MSP1 protein, S cerevisiaeSaccharomyces cerevisiae ProteinsAAA proteinscell biologycryo-EME. colihumanmitochondriamolecular biophysicsprotein mislocalizationprotein quality controlstructural biologytail-anchored proteins

Identifiers

PMID35550246
PMCPMC9273213
OpenAlexW4280527068

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.