ArticleMalaria journal2022
Challenges and lessons learned during the planning and early implementation of the RTS,S/AS01
Article in Malaria journal, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
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The trial behind it
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Who cites it
27 citing papers in PubMed.
- Healthcare workers' knowledge and acceptance of the malaria vaccine in the Nanoro Health District of Burkina Faso: a cross-sectional study.Malaria journal · 2026Article
- Community perspective on feasibility of malaria mass drug administration: a qualitative evidence from the Eastern Region of Ghana.Malaria journal · 2026Article
- Timing of the fourth dose of RTS,S/AS01 malaria vaccine in perennial settings: a modelling study.Malaria journal · 2026Article
- Mapping stakeholders' positioning in the access and delivery partnership value chain: the case of the RTS,S malaria vaccine introduction in Ghana.International journal of public health · 2026Article
- Effectiveness of the Smart Home Model for Integrated Malaria Prevention: A Case-Control Study in Oyam District, Uganda.Journal of tropical medicine · 2026Article
- Untangling choices: how awareness and socio-economic status shape malaria vaccination decisions among Ghanaian women.Malaria journal · 2025Article
- General knowledge and attitude of healthcare professionals and infrastructural readiness prior to implementation of malaria vaccine in selected hospitals in Tororo district, Uganda: a cross-sectional study.BMC public health · 2025Article
- Costs, delivery strategies and implementation challenges for malaria vaccines: a rapid review of literature.Tropical diseases, travel medicine and vaccines · 2025Review
- Subnational introduction of the RTS,S/AS01Malaria journal · 2025Article
- Mitigation of Malaria in Sub-Saharan Africa through Vaccination: A Budding Road Map for Global Malaria Eradication.Ethiopian journal of health sciences · 2025Review
- Review
- Factors associated with vaccine default in Southern Ghana based on data from the RTSS malaria vaccine trial in Cape Coast.Scientific reports · 2025Article
- National human papillomavirus vaccination (GH_PV) programme: Ghana at a crossroads; is vaccine supply alone enough to ensure success?Frontiers in global women's health · 2025Article
- Current Developments in Malaria Vaccination: A Concise Review on Implementation, Challenges, and Future Directions.Clinical pharmacology : advances and applications · 2025Review
- Performance characteristics and potential public health impact of improved pre-erythrocytic malaria vaccines targeting childhood burden.PLOS global public health · 2025Article
- Trend of RTS,S vaccine uptake in the malaria vaccine implementing programme (MVIP) pilot regions, Ghana; 2019-2022.Heliyon · 2024Article
- The impact of the RTS,S malaria vaccine on uncomplicated malaria: evidence from the phase IV study districts, Upper East Region, Ghana, 2020-2022.Malaria journal · 2024Article
- Malaria vaccine efficacy, safety, and community perception in Africa: a scoping review of recent empirical studies.Infection · 2024Article
- Human papilloma virus vaccination in the resource-limited settings of sub-Saharan Africa: Challenges and recommendations.Vaccine: X · 2024Review
- Policy uptake and implementation of the RTS,S/AS01 malaria vaccine in sub-Saharan African countries: status 2 years following the WHO recommendation.BMJ global health · 2024Review
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
backgroundIn 2019, the RTS,S/AS01
methodsTwenty-one in-depth interviews were conducted with regional and district health service managers and frontline health workers three months after the start of MVIP in May 2019. Data were coded using NVivo software version 12 and a coding framework was developed to support thematic analysis to identify the challenges and lessons learned during the RTS,S/AS01
resultsParticipants reported challenges related to the characteristics of the intervention, such as issues with the vaccine schedule and eligibility criteria, and challenges related to how it was implemented as a pilot programme. Additionally, major challenges were faced due to the spread of rumours leading to vaccine refusals; thus, the outer setting of the CFIR was adapted to accommodate rumours within the community context. Health service managers and frontline health workers also experienced challenges with the process of implementing RTS,S/AS01
conclusionsThis study identified 12 main challenges and lessons learned by health service managers and health workers during the planning and early implementation phases of the RTS,S/AS01
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.