Evidence map›Paper›PMID 35549947›Full record

ArticleJournal of nanobiotechnology2022

All-in-one approaches for triple-negative breast cancer therapy: metal-phenolic nanoplatform for MR imaging-guided combinational therapy.

Qi Xie, Shichao Li, Xingxing Feng, Jingyu Shi, Yang Li, Guanjie Yuan, Conglian Yang, Yaqi Shen, Li Kong, Zhiping Zhang

Open access · goldAbstract read
In one paragraph

Article in Journal of nanobiotechnology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
1.9field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 26 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Review
  4. Article
  5. Article
  6. Review
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Qi XieTongji School of Pharmacy, Huazhong University of Science and Technology, Wuhan, 430030, China.
Shichao LiDepartment of Radiology, Tongji Hospital of Tongji Medical College of Huazhong University of Science and Technology, Wuhan, 430030, China.
Xingxing FengTongji School of Pharmacy, Huazhong University of Science and Technology, Wuhan, 430030, China.
Jingyu ShiLiyuan Hospital of Tongji Medical College of Huazhong University of Science and Technology, Wuhan, 430030, China.
Yang LiTongji School of Pharmacy, Huazhong University of Science and Technology, Wuhan, 430030, China.
Guanjie YuanDepartment of Radiology, Tongji Hospital of Tongji Medical College of Huazhong University of Science and Technology, Wuhan, 430030, China.
Conglian YangTongji School of Pharmacy, Huazhong University of Science and Technology, Wuhan, 430030, China.
Yaqi ShenDepartment of Radiology, Tongji Hospital of Tongji Medical College of Huazhong University of Science and Technology, Wuhan, 430030, China. yqshen@hust.edu.cn.
Li KongTongji School of Pharmacy, Huazhong University of Science and Technology, Wuhan, 430030, China. kongl@hust.edu.cn.
Zhiping ZhangTongji School of Pharmacy, Huazhong University of Science and Technology, Wuhan, 430030, China. zhipingzhang@mail.hust.edu.cn.
Huazhong University of Science and Technology · CNTongji Hospital · CN

Funding

National Natural Science Foundation of China 32101144National Natural Science Foundation of China 81673374National Natural Science Foundation of China 82071890Natural Science Foundation of Hubei Province 2020CFB301Program for HUST Academic Frontier Youth Team 2018QYTD13
6 · The paper itself

Abstract

backgroundConventional chemotherapy has poor efficacy in triple-negative breast cancer (TNBC) which is highly heterogeneous and aggressive. Imaging-guided therapy is usually combined with diverse treatment modalities, could realize the integration of diagnosis and treatments. Therefore, the primary challenge for combinational therapy is designing proper delivery systems to accomplish multiple synergistic effects.

resultsHerein, a facile nanoplatform was manufactured to fulfill the all-in-one approaches for TNBC combinational therapy. Fe

conclusionsA nano-system that integrated imaging and combinational therapy (chemotherapy, chemodynamic therapy and photothermal therapy) were developed to kill the tumor and monitor therapeutic efficacy. This strategy provided an all-in-one theranostic nanoplatform for MRI-guided combinational therapy against TNBC.

Indexed as

NanoparticlesNeoplasmsTriple Negative Breast NeoplasmsCell Line, TumorContrast MediaDrug CarriersHumansMagnetic Resonance ImagingPhototherapyPhotothermal TherapySerum Albumin, BovineContrast MediaDrug CarriersSerum Albumin, BovineBleomycinChemodynamic therapyMPNsMRISelf-assembly

Identifiers

PMID35549947
PMCPMC9097361
OpenAlexW4280525101

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.