ArticleBMC microbiology2022
Antimicrobial activity of supernatants produced by bacteria isolated from Brazilian stingless bee's larval food.
Article in BMC microbiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed, 14 citations in OpenAlex.
- Bacterial polar metabolites modulate β-amyloid toxicity and cholinergic dysfunction in models of Alzheimer's disease.Scientific reports · 2026Article
- Microbial synthesis of silver nanoparticles using bacterial supernatants from Brazilian stingless bees with antimicrobial activity.Scientific reports · 2026Article
- In vitro effects of Bacillus velezensis strain Mandacaium against Xanthomonas citri pv. glycines: genomic and metabolomic insights.Scientific reports · 2026Article
- Genome-resolved metagenomics reveals a phylogenetically cohesiveISME communications · 2026Article
- In silico interactome analysis reveals distinct and complementary metabolic roles of bacteria in stingless bee larval food.Computational and structural biotechnology journal · 2026Article
- Distinct colony niches shape associated microbiotas in Neotropical stingless bees.Genetics and molecular biology · 2026Article
- Screening of Microorganisms Isolated from Stingless Bees' Larval Food in the Biocontrol ofJournal of nematology · 2025Article
- Green synthesis of silver nanoparticle using pollen extract from Tetragonisca angustula a stingless bee.Discover nano · 2024Article
- Bacteria, yeasts, and fungi associated with larval food of Brazilian native stingless bees.Scientific reports · 2023Article
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe discovery of new molecules with antimicrobial properties has been a promising approach, mainly when related to substances produced by bacteria. The use of substances produced by bees has evidenced the antimicrobial action in different types of organisms. Thus, the use of bacteria isolated from larval food of stingless bees opens the way for the identification of the new molecules. The effect of supernatants produced by these bacteria was evaluated for their ability to inhibit the growth of bacteria of clinical interest. Furthermore, their effects were evaluated when used in synergy with antibiotics available in the pharmaceutical industry.
resultsA few supernatants showed an inhibitory effect against susceptible and multiresistant strains in the PIC assay and the modulation assay. Emphasizing the inhibitory effect on multidrug-resistant strains, 7 showed an effect on multidrug-resistant Escherichia coli (APEC), Klebsiella pneumoniae carbapenemase (KPC), multidrug-resistant Pseudomonas aeruginosa, and multidrug-resistant Staphylococcus aureus (MRSA) in the PIC assay. Of the supernatants analyzed, some presented synergism for more than one species of multidrug-resistant bacteria. Nine had a synergistic effect with ampicillin on E. coli (APEC) or S. aureus (MRSA), 5 with penicillin G on E. coli (APEC) or KPC, and 3 with vancomycin on KPC.
conclusionIn summary, the results indicate that supernatants produced from microorganisms can synthesize different classes of molecules with potent antibiotic activity against multiresistant bacteria. Thus, suggesting the use of these microorganisms for use clinical tests to isolate the molecules produced and their potential for use.
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