Evidence map›Paper›PMID 35549799›Full record

ReviewLeukemia & lymphoma2022

Lack of a caregiver is associated with shorter survival in myeloma patients undergoing autologous stem cell transplantation.

Morie A Gertz, Rahma Warsame, Eli Muchtar, Frances Buadi, Angela Dispenzieri, Wilson Gonsalves, David Dingli, Suzanne Hayman, Prashant Kapoor, Taxiarchis Kourelis and 3 more

Open access · greenAbstract readReview
In one paragraph

Review in Leukemia & lymphoma, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Trial
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 1 institution in 1 country.

Morie A GertzDivision of Hematology, Mayo Clinic, Rochester, MN, USA.ORCID 0000-0002-3853-5196
Rahma WarsameDivision of Hematology, Mayo Clinic, Rochester, MN, USA.
Eli MuchtarDivision of Hematology, Mayo Clinic, Rochester, MN, USA.ORCID 0000-0003-2210-2174
Frances BuadiDivision of Hematology, Mayo Clinic, Rochester, MN, USA.
Angela DispenzieriDivision of Hematology, Mayo Clinic, Rochester, MN, USA.ORCID 0000-0001-8780-9512
Wilson GonsalvesDivision of Hematology, Mayo Clinic, Rochester, MN, USA.
David DingliDivision of Hematology, Mayo Clinic, Rochester, MN, USA.
Suzanne HaymanDivision of Hematology, Mayo Clinic, Rochester, MN, USA.
Prashant KapoorDivision of Hematology, Mayo Clinic, Rochester, MN, USA.
Taxiarchis KourelisDivision of Hematology, Mayo Clinic, Rochester, MN, USA.
Shaji K KumarDivision of Hematology, Mayo Clinic, Rochester, MN, USA.ORCID 0000-0001-5392-9284
Martha Q LacyDivision of Hematology, Mayo Clinic, Rochester, MN, USA.
William HoganDivision of Hematology, Mayo Clinic, Rochester, MN, USA.ORCID 0000-0002-5841-4105
Mayo Clinic in Arizona · US

Funding

Project 4: Targeting Resistance to T-Cell Directed Therapy in Multiple MyelomaP50CA186781 · NCI · MAYO CLINIC ARIZONA · PI Peter Leif Bergsagel · 2015 to 2026
$25.5M
NCI NIH HHS P50 CA186781
6 · The paper itself

Abstract

There is increasing evidence that social infrastructure and a healthy social network can improve cancer survival. Mayo Clinic has an outpatient stem cell transplantation program for myeloma. Safe outpatient transplantation requires a caregiver to be present. Patients lacking a caregiver are transplanted as an inpatient. We reviewed outcomes on over 2000 patients with multiple myeloma, 2103 transplanted as an outpatient compared with 41 hospitalized for transplantation. Although progression-free survival following transplantation was identical between the two groups, overall survival was shorter in those hospitalized. This suggests that the absence of a caregiver for transplantation is an important surrogate of the social infrastructure associated with poor outcomes in transplanted patients with multiple myeloma.

Indexed as

Hematopoietic Stem Cell TransplantationMultiple MyelomaCaregiversDisease-Free SurvivalHumansStem Cell TransplantationTransplantation, Autologouscancer outcomesfamily supportMultiple myelomasocial connectednessstem cell transplantation

Identifiers

PMID35549799
PMCPMC9679915
OpenAlexW4280616482

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.