Evidence map›Paper›PMID 35549707›Full record

ArticleEnvironmental health : a global access science source2022

Residential greenness, asthma, and lung function among children at high risk of allergic sensitization: a prospective cohort study.

Kim Hartley, Patrick H Ryan, Gordon L Gillespie, Joseph Perazzo, J Michael Wright, Glenn E Rice, Geoffrey H Donovan, Rebecca Gernes, Gurjit K Khurana Hershey, Grace LeMasters and 1 more

Abstract read
In one paragraph

Article in Environmental health : a global access science source, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Association between residential greenness and allergic diseases among adolescents in South Korea: A nationwide representative study.Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology · 2025
    Article
  5. Article
  6. Article
  7. Feeling Connected to Nature Attenuates the Association between Complicated Grief and Mental Health.International journal of environmental research and public health · 2024
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Advancing Exposomic Research in Prenatal Respiratory Disease Programming.Immunology and allergy clinics of North America · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Kim HartleyCincinnati Children's Hospital Medical Center, 3333 Burnet Avenue, Cincinnati, OH, 45229, USA. Kim.Hartley@cchmc.org.ORCID 0000-0002-4948-0872
Patrick H RyanCincinnati Children's Hospital Medical Center, 3333 Burnet Avenue, Cincinnati, OH, 45229, USA.
Gordon L GillespieCollege of Nursing, University of Cincinnati, 3110 Vine St, Cincinnati, OH, 45219, USA.
Joseph PerazzoCollege of Nursing, University of Cincinnati, 3110 Vine St, Cincinnati, OH, 45219, USA.
J Michael WrightToxic Effects Assessment Branch (Cincinnati), Chemical and Pollutant Assessment Division, Center for Public Health and Environmental Assessment (CPHEA), Office of Research and Development, U.S. Environmental Protection Agency, 26 West M.L. King Drive, Cincinnati, OH, 45268, USA.
Glenn E RiceToxic Effects Assessment Branch (Cincinnati), Chemical and Pollutant Assessment Division, Center for Public Health and Environmental Assessment (CPHEA), Office of Research and Development, U.S. Environmental Protection Agency, 26 West M.L. King Drive, Cincinnati, OH, 45268, USA.
Geoffrey H DonovanUSDA Forest Service, PNW Research Station, 1220 SW 3rd Ave, Portland, OR, 97204, USA.
Rebecca GernesAssociation of Schools and Programs of Public Health (ASPPH), Environmental Health Research Participant, 2014-2016, 1900 M St NW #710, DC, 20036, Washington, USA.
Gurjit K Khurana HersheyCincinnati Children's Hospital Medical Center, 3333 Burnet Avenue, Cincinnati, OH, 45229, USA.
Grace LeMastersCollege of Medicine, University of Cincinnati, 3230 Eden Ave, Cincinnati, OH, 45267, USA.
Cole BrokampCincinnati Children's Hospital Medical Center, 3333 Burnet Avenue, Cincinnati, OH, 45229, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWhile benefits of greenness to health have been reported, findings specific to child respiratory health are inconsistent.

methodsWe utilized a prospective birth cohort followed from birth to age 7 years (n = 617). Residential surrounding greenness was quantified via Normalized Difference Vegetation Index (NDVI) within 200, 400, and 800 m distances from geocoded home addresses at birth, age 7 years, and across childhood. Respiratory health outcomes were assessed at age 7 years, including asthma and lung function [percent predicted forced expiratory volume in the first second (%FEV

resultsWe noted evidence of positive confounding as inverse associations were attenuated upon adjustment in the multivariable models. We found evidence of effect measure modification of NDVI and asthma within 400 m at age 7 years by atopic status (p = 0.04), whereby children sensitized to common allergens were more likely to develop asthma as exposure to greenness increased (OR = 1.3, 95% CI: 0.9, 2.0) versus children not sensitized to common allergens (OR = 0.8, 95% CI: 0.5, 1.2). We found consistently positive associations between NDVI and %FEV

conclusionSensitivity to allergens may modify the effect of greenness on risk for asthma in children but greenness is likely beneficial for concurrent lung function regardless of allergic status.

Indexed as

Air PollutionAsthmaAllergensChildHumansInfant, NewbornLungProspective StudiesAllergensAllergyAtopyChildEnvironmentGreen spaceGreenspacePediatricRespiratory

Identifiers

PMID35549707
PMCPMC9097404

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.