ArticleBMC biology2022
Nutritional control regulates symbiont proliferation and life history in coral-dinoflagellate symbiosis.
Article in BMC biology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed.
- Rapid coral bleaching recovery via symbiont transfer from healthy corals.Science advances · 2026Article
- Advancing Symbiodiniaceae Functional Ecology Through a Trait-Based Framework.Ecology and evolution · 2026Review
- Trophic Antioxidant Transfer as a Measure for Scalable Coral Conservation Strategies.Antioxidants (Basel, Switzerland) · 2026Article
- Heat-evolved coral photosymbionts exhibit dampened stress responses across distinct physiological contexts.The New phytologist · 2026Article
- Seasonal Physiological Strategies Reveal Contrasting Host-Symbiont Dynamics Among Dominant Indo-Pacific Reef-Building Corals.Ecology and evolution · 2026Article
- Dual urea utilization enzyme systems in Symbiodiniaceae coral symbionts under warming.BMC biology · 2026Article
- Heterotrophy and symbiosis affect energy reserves for pedal lacerates in the sea anemonePeerJ · 2026Article
- Physiology and metabolism of eukaryotic microalgae involved in aquatic photosymbioses.The New phytologist · 2025Review
- Moderate levels of dissolved iron stimulate cellular growth and increase lipid storage in Symbiodinium sp.Journal of phycology · 2025Article
- Stability of the cnidarian-dinoflagellate symbiosis is primarily determined by symbiont cell-cycle arrest.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Ammonium supply represses iron limitation to support Symbiodiniaceae growth.Frontiers in microbiology · 2025Article
- Genomes of the Caribbean reef-building coralsbioRxiv : the preprint server for biology · 2024Article
- Osmotic stress response of the coral and oyster pathogenApplied and environmental microbiology · 2024Article
- Coordinated wound responses in a regenerative animal-algal holobiont.Nature communications · 2024Article
- Irradiance driven trophic plasticity in the coral Madracis pharensis from the Eastern Mediterranean.Scientific reports · 2024Article
- Coupled carbon and nitrogen cycling regulates the cnidarian-algal symbiosis.Nature communications · 2023Article
- A carbon-nitrogen negative feedback loop underlies the repeated evolution of cnidarian-Symbiodiniaceae symbioses.Nature communications · 2023Article
- Chemical mutagenesis and thermal selection of coral photosymbionts induce adaptation to heat stress with trait trade-offs.Evolutionary applications · 2023Article
- Transcriptomic Analysis of the Response of the Toxic DinoflagellateMicroorganisms · 2023Article
- Molecular insights into the Darwin paradox of coral reefs from the sea anemone Aiptasia.Science advances · 2023Article
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Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe coral-Symbiodiniaceae symbiosis is fundamental for the coral reef ecosystem. Corals provide various inorganic nutrients to their algal symbionts in exchange for the photosynthates to meet their metabolic demands. When becoming symbionts, Symbiodiniaceae cells show a reduced proliferation rate and a different life history. While it is generally believed that the animal hosts play critical roles in regulating these processes, far less is known about the molecular underpinnings that allow the corals to induce the changes in their symbionts.
resultsWe tested symbiont cell proliferation and life stage changes in vitro in response to different nutrient-limiting conditions to determine the key nutrients and to compare the respective symbiont transcriptomic profiles to cells in hospite. We then examined the effects of nutrient repletion on symbiont proliferation in coral hosts and quantified life stage transitions in vitro using time-lapse confocal imaging. Here, we show that symbionts in hospite share gene expression and pathway activation profiles with free-living cells under nitrogen-limited conditions, strongly suggesting that symbiont proliferation in symbiosis is limited by nitrogen availability.
conclusionsWe demonstrate that nitrogen limitation not only suppresses cell proliferation but also life stage transition to maintain symbionts in the immobile coccoid stage. Nutrient repletion experiments in corals further confirmed that nitrogen availability is the major factor limiting symbiont density in hospite. Our study emphasizes the importance of nitrogen in coral-algae interactions and, more importantly, sheds light on the crucial role of nitrogen in symbiont life history regulation.
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