Evidence map›Paper›PMID 35549655›Full record

ArticleAmerican journal of respiratory and critical care medicine2022

Therapeutic Targeting of the Respiratory Microbiome.

Sanjay H Chotirmall, Debby Bogaert, James D Chalmers, Michael J Cox, Philip M Hansbro, Yvonne J Huang, Philip L Molyneaux, David N O'Dwyer, Alexa A Pragman, Geraint B Rogers and 2 more

Open access · greenAbstract read
In one paragraph

Article in American journal of respiratory and critical care medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 50 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
50citing papers in PubMed, 1 pooled it
7.0field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

50 citing papers in PubMed, 1 synthesis or guideline pooled it, 84 citations in OpenAlex.

  1. Pooled it
  2. Can Treatable Traits Be the Approach to Addressing the Complexity and Heterogeneity of COPD?International journal of chronic obstructive pulmonary disease · 2023
    Trial
  3. Review
  4. Article
  5. Review
  6. Review
  7. Article
  8. Upper and Lower Respiratory Tract Compartmentalization in Pediatric Stem Cell Transplantation.American journal of respiratory cell and molecular biology · 2026
    Article
  9. Article
  10. Article
  11. Targeted lungScience advances · 2026
    Article
  12. Article
  13. Multi-omics to study chronic respiratory diseases and viral infections.European respiratory review : an official journal of the European Respiratory Society · 2026
    Review
  14. Article
  15. Article
  16. Article
  17. Allergic bronchopulmonary aspergillosis andJournal of thoracic disease · 2025
    Review
  18. Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 10 institutions in 5 countries.

Sanjay H ChotirmallLee Kong Chian School of Medicine, Nanyang Technological University, Singapore.ORCID 0000-0003-0417-7607
Debby BogaertCenter for Inflammation Research, University of Edinburgh, Edinburgh, United Kingdom.
James D ChalmersDivision of Molecular and Clinical Medicine, University of Dundee, Dundee, United Kingdom.
Michael J CoxInstitute of Microbiology and Infection, University of Birmingham, Birmingham, United Kingdom.ORCID 0000-0002-4002-1506
Philip M HansbroCentre for Inflammation, Centenary Institute and University of Technology Sydney, Sydney, New South Wales, Australia.
Yvonne J HuangDivision of Pulmonary and Critical Care Medicine, Department of Medicine, and.
Philip L MolyneauxNational Heart and Lung Institute, Imperial College London, London, United Kingdom.
David N O'DwyerDivision of Pulmonary and Critical Care Medicine, Department of Medicine, and.ORCID 0000-0003-3214-380X
Alexa A PragmanDepartment of Medicine, Minneapolis Veterans Affairs Medical Center, Minneapolis, Minnesota.ORCID 0000-0001-8152-3951
Geraint B RogersMicrobiome and Host Health, South Australian Health and Medical Research Institute, Adelaide, South Australia, Australia.
Leopoldo N SegalDivision of Pulmonary, Critical Care, and Sleep Medicine, New York University Grossman School of Medicine, NYU Langone Health, New York, New York; and.
Robert P DicksonDivision of Pulmonary and Critical Care Medicine, Department of Medicine, and.ORCID 0000-0002-6875-4277
University of Michigan · USFlinders University · AUImperial College London · GBNanyang Technological University · SGNYU Langone Health · USUniversity Medical Center Utrecht · NLUniversity of Birmingham · GBUniversity of Dundee · GBUniversity of Minnesota · USUniversity of Technology Sydney · AU

Funding

University of Minnesota Clinical and Translational Science Institute (UMN CTSI)UL1TR002494 · NCATS · UNIVERSITY OF MINNESOTA · PI BLAZAR, BRUCE R, WEISDORF, DANIEL J · 2018 to 2022
$34.9M
PULMONARY CELLULAR AND MOLECULAR BIOLOGY TRAININGT32HL007749 · NHLBI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Robert Pickett Dickson · 1993 to 2026
$19.9M
Local microbiota signatures of pro-tumor immunity and checkpoint inhibition susceptibility in lung cancerR37CA244775 · NCI · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI Leopoldo Nicolas Segal · 2020 to 2026
$4.7M
Sputum Microbial Markers of Type 2-Low AsthmaR01AI129958 · NIAID · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI HUANG, YVONNE JEAN · 2017 to 2021
$3.6M
The role of the lung microbiome in oxygen-induced lung injuryR01HL144599 · NHLBI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI DICKSON, ROBERT PICKETT · 2019 to 2023
$2.1M
Toll-like Receptors and Respiratory Microbiota Interactions in Idiopathic PulmonaryR00HL139996 · NHLBI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI O'DWYER, DAVID NOEL · 2020 to 2022
$747k
Midcareer Investigator Award in Patient-Oriented Research in the Microbiome and Lung DiseaseK24HL159247 · NHLBI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Robert Pickett Dickson · 2022 to 2026
$625k
Gut Microbiota and Host Regulatory Cross-Talk in Pulmonary FibrosisR56HL155055 · NHLBI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI O'DWYER, DAVID NOEL · 2021 to 2021
$477k
Microbial Dysbiosis Among Veterans Following Deployment-Related Airborne ExposuresI01CX002130 · VA · MINNEAPOLIS VA MEDICAL CENTER · PI ALEXA A PRAGMAN · 2022 to 2026
–
Evaluation of the Oral and Lung Microbiota and Inflammation in Chronic Obstructive Pulmonary Disease Frequent ExacerbatorsIK2CX001095 · VA · MINNEAPOLIS VA MEDICAL CENTER · PI PRAGMAN, ALEXA A · 2016 to 2021
–
Chief Scientist Office SCAF/16/03Chief Scientist Office SCAF/17/03CSRD VA I01 CX002130CSRD VA IK2 CX001095NCATS NIH HHS UL1 TR002494NCI NIH HHS R37 CA244775NHLBI NIH HHS R00 HL139996NHLBI NIH HHS R01 HL144599NHLBI NIH HHS R56 HL155055NHLBI NIH HHS T32 HL007749NIAID NIH HHS R01 AI129958NIH HHS R00HL139996NIH HHS R01AI129958NIH HHS R01HL144599NIH HHS R37CA244775NIH HHS R56HL155055NIH HHS T32HL007749NIH HHS UL1TR002494
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

MicrobiotaRespiratory SystemHumans

Identifiers

PMID35549655
PMCPMC9716896
OpenAlexW4280518892

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.