Evidence map›Paper›PMID 35549518›Full record

ArticleBone & joint research2022

Impact of racial disparities and insurance status in patients with bone sarcomas in the USA : a population-based cohort study.

Xianglin Hu, Tomohiro Fujiwara, Matthew T Houdek, Lingxiao Chen, Wending Huang, Zhengwang Sun, Yangbai Sun, Wangjun Yan

Abstract read
In one paragraph

Article in Bone & joint research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Disparities in Musculoskeletal Oncology.Current reviews in musculoskeletal medicine · 2024
    Review
  6. Article
  7. Article
  8. Article
  9. Birth characteristics and risk of Ewing sarcoma.Cancer causes & control : CCC · 2023
    Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Xianglin HuDepartment of Musculoskeletal Surgery, Fudan University Shanghai Cancer Center, Shanghai, China.ORCID 0000-0002-8099-8725
Tomohiro FujiwaraDepartment of Orthopaedic Surgery, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences, Okayama, Japan.
Matthew T HoudekDepartment of Orthopaedic Surgery, Mayo Clinic, Rochester, Minnesota, USA.ORCID 0000-0003-0390-1018
Lingxiao ChenFaculty of Medicine and Health, University of Sydney, The Kolling Institute, Sydney, Australia.
Wending HuangDepartment of Musculoskeletal Surgery, Fudan University Shanghai Cancer Center, Shanghai, China.ORCID 0000-0002-8473-3003
Zhengwang SunDepartment of Musculoskeletal Surgery, Fudan University Shanghai Cancer Center, Shanghai, China.ORCID 0000-0002-7728-3999
Yangbai SunDepartment of Musculoskeletal Surgery, Fudan University Shanghai Cancer Center, Shanghai, China.ORCID 0000-0002-2853-2813
Wangjun YanDepartment of Musculoskeletal Surgery, Fudan University Shanghai Cancer Center, Shanghai, China.ORCID 0000-0001-9178-0687

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimsSocioeconomic and racial disparities have been recognized as impacting the care of patients with cancer, however there are a lack of data examining the impact of these disparities on patients with bone sarcoma. The purpose of this study was to examine socioeconomic and racial disparities that impact the oncological outcomes of patients with bone sarcoma.

methodsWe reviewed 4,739 patients diagnosed with primary bone sarcomas from the Surveillance, Epidemiology and End Results (SEER) registry between 2007 and 2015. We examined the impact of race and insurance status associated with the presence of metastatic disease at diagnosis, treatment outcome, and overall survival (OS).

resultsPatients with Medicaid (odds ratio (OR) 1.41; 95% confidence interval (CI) 1.15 to 1.72) and uninsured patients (OR 1.90; 95% CI 1.26 to 2.86) had higher risks of metastatic disease at diagnosis compared to patients with health insurance. Compared to White patients, Black (OR 0.63, 95% CI 0.47 to 0.85) and Asian/Pacific Islander (OR 0.65, 95% CI 0.46 to 0.91) were less likely to undergo surgery. In addition, Black patients were less likely to receive chemotherapy (OR 0.67, 95% CI 0.49 to 0.91) compared to White patients. In patients with chondrosarcoma, those with Medicaid had worse OS compared to patients with insurance (hazard ratio (HR) 1.65, 95% CI 1.06 to 2.56).

conclusionIn patients with a bone sarcoma, the cancer stage at diagnosis varied based on insurance status, and racial disparities were identified in treatment. Further studies are needed to identify modifiable factors which can mitigate socioeconomic and racial disparities found in patients with bone sarcomas. Cite this article:

Indexed as

Bone sarcomabone sarcomasCancer disparitycancerschemotherapyChondrosarcomasEpidemiologyEwing sarcomaHealth equalityInsurancemalignant bone tumoursmetastatic diseaseosteosarcomasPrimary bone sarcomasRacial disparities

Identifiers

PMID35549518
PMCPMC9130676

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.