Evidence map›Paper›PMID 35549283›Full record

ArticleThe Journal of organic chemistry2022

Telescoped Oxidation and Cycloaddition of Urazoles to Access Diazacyclobutenes.

Brock A Miller, Chandima J Narangoda, Thomas L Johnson, Ryan D Barata, Flavoris Belue, Erin E Solomon, Alexis A Bragg, Daniel C Whitehead

Open access · greenAbstract read
In one paragraph

Article in The Journal of organic chemistry, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.8field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Brock A MillerDepartment of Chemistry, Clemson University, Clemson, South Carolina 29631, United States.ORCID 0000-0002-1368-0530
Chandima J NarangodaDepartment of Chemistry, Faculty of Applied Sciences, University of Sri Jayewardenepura, Gangodawila, Nugegoda-10250, Sri Lanka.ORCID 0000-0002-5690-2420
Thomas L JohnsonSchool of Medicine-Greenville, University of South Carolina, Greenville, South Carolina 29605, United States.
Ryan D BarataDepartment of Chemistry, Clemson University, Clemson, South Carolina 29631, United States.
Flavoris BelueDepartment of Chemistry, Clemson University, Clemson, South Carolina 29631, United States.
Erin E SolomonDepartment of Chemistry, Clemson University, Clemson, South Carolina 29631, United States.
Alexis A BraggDepartment of Chemistry, Clemson University, Clemson, South Carolina 29631, United States.
Daniel C WhiteheadDepartment of Chemistry, Clemson University, Clemson, South Carolina 29631, United States.ORCID 0000-0001-6881-2628
Clemson University · USUniversity of South Carolina · USUniversity of Sri Jayewardenepura · LK

Funding

The role of acetate fermentation in Entamoeba histolytica growth and infectionP20GM109094 · NIGMS · CLEMSON UNIVERSITY · PI KOZUBOWSKI, LUKASZ · 2016 to 2020
$10.4M
Immunology and Microbial Pathogenesis Research Training ProgramT32AI134632 · NIAID · WEILL MEDICAL COLL OF CORNELL UNIV · PI EHRT, SABINE, LI, MING · 2019 to 2023
$747k
MENTOR: Medical Enrichment Through Opportunities in ResearchT35AI134643 · NIAID · CLEMSON UNIVERSITY · PI SMITH, KERRY SCOT · 2018 to 2023
$118k
NIAID NIH HHS T32 AI134632NIAID NIH HHS T35 AI134643NIGMS NIH HHS P20 GM109094
6 · The paper itself

Abstract

Our previous method to access the diazacyclobutene scaffold did not allow for modification of the substituent originating from the 1,2,4-triazoline-3,5-dione component. We have circumvented this challenge and expanded access to additional structural diversity of the scaffold. A telescoped urazole oxidation and Lewis acid-catalyzed cyclization provided R

Indexed as

TriazolesCyclizationCycloaddition ReactionMolecular StructureTriazolesurazole

Identifiers

PMID35549283
PMCPMC10263296
OpenAlexW4280603982

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.