Evidence map›Paper›PMID 35548907›Full record

ArticleOrganic & biomolecular chemistry2022

Development of an ATP-independent bioluminescent probe for detection of extracellular hydrogen peroxide.

Justin J O'Sullivan, Marie C Heffern

Open access · greenAbstract read
In one paragraph

Article in Organic & biomolecular chemistry, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 5 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Justin J O'SullivanDepartment of Chemistry, University of California Davis, One Shields Drive, Davis, CA 95616, USA. mcheffern@ucdavis.edu.ORCID 0000-0003-0264-7783
Marie C HeffernDepartment of Chemistry, University of California Davis, One Shields Drive, Davis, CA 95616, USA. mcheffern@ucdavis.edu.ORCID 0000-0001-7501-2741
University of California, Davis · US

Funding

Supplement: Metalloendocrinology: Mapping Bioinorganic Chemistry in the Extracellular SpaceR35GM133684 · NIGMS · UNIVERSITY OF CALIFORNIA AT DAVIS · PI HEFFERN, MARIE C. · 2019 to 2023
$2.0M
National Science Foundation 2048265NIGMS NIH HHS 5R35GM133684-02NIGMS NIH HHS R35 GM133684
6 · The paper itself

Abstract

This work reports a new ATP-independent bioluminescent probe (bor-DTZ) for detecting hydrogen peroxide that is compatible with the Nanoluciferase enzyme. The probe is designed with an arylboronate ester protecting group appended to a diphenylterazine core

Indexed as

Adenosine TriphosphateHydrogen PeroxideFluorescent DyesHumansMCF-7 CellsReactive Oxygen SpeciesAdenosine TriphosphateFluorescent DyesHydrogen PeroxideReactive Oxygen Species

Identifiers

PMID35548907
PMCPMC9378503
OpenAlexW4280644119

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.