Efficient and divergent synthesis of polyfunctionalized 2-pyridones from β-keto amides.

Baochang Gao, Yufeng Sun, Jun Wang, Zhigang Yuan, Liwu Zu, Xu Zhang, Wenbin Liu

Abstract read

In one paragraph

Article in RSC advances, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Baochang GaoInstitute of Composite Materials, Key Laboratory of Superlight Material and Surface Technology of Ministry of Education, College of Materials Science and Chemical Engineering, Harbin Engineering University Harbin 150001 P. R. China chemgbc@hrbeu.edu.cn liuwenbin@hrbeu.edu.cn.ORCID https://orcid.org/0000-0002-9161-6585

Yufeng SunDaqing Branch of Heilongjiang Academy of Sciences Daqing 163319 P. R. China.

Jun WangInstitute of Composite Materials, Key Laboratory of Superlight Material and Surface Technology of Ministry of Education, College of Materials Science and Chemical Engineering, Harbin Engineering University Harbin 150001 P. R. China chemgbc@hrbeu.edu.cn liuwenbin@hrbeu.edu.cn.

Zhigang YuanDaqing Branch of Heilongjiang Academy of Sciences Daqing 163319 P. R. China.

Liwu ZuInstitute of Composite Materials, Key Laboratory of Superlight Material and Surface Technology of Ministry of Education, College of Materials Science and Chemical Engineering, Harbin Engineering University Harbin 150001 P. R. China chemgbc@hrbeu.edu.cn liuwenbin@hrbeu.edu.cn.

Xu ZhangDaqing Branch of Heilongjiang Academy of Sciences Daqing 163319 P. R. China.

Wenbin LiuInstitute of Composite Materials, Key Laboratory of Superlight Material and Surface Technology of Ministry of Education, College of Materials Science and Chemical Engineering, Harbin Engineering University Harbin 150001 P. R. China chemgbc@hrbeu.edu.cn liuwenbin@hrbeu.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Efficient and divergent one-pot synthesis of polyfunctionalized 2-pyridones from β-keto amides based on reaction condition selection was developed. The methodology offers several significant advantages including mild conditions, ease of handling, high yields, and a relatively broad range of substrates. Based on various experiments and observations, a plausible mechanism for the selective synthesis of 2-pyridones was proposed.

Identifiers

PMID35548816

DOI10.1039/c8ra05709e

PMCPMC9086556

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.