Evidence map›Paper›PMID 35548696›Full record

ReviewFrontiers in behavioral neuroscience2022

The Value of Patient Registries to Advance Basic and Translational Research in the Area of Traumatic Brain Injury.

Melissa C Duff, Emily L Morrow, Malcolm Edwards, Ryan McCurdy, Sharice Clough, Nirav Patel, Kimberly Walsh, Natalie V Covington

Abstract readReview
In one paragraph

Review in Frontiers in behavioral neuroscience, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

  1. Trial
  2. Article
  3. Moderate-severe traumatic brain injury disrupts core mechanisms of online language processing and use.Cortex; a journal devoted to the study of the nervous system and behavior · 2026
    Article
  4. Reduced temporal organization of narrative recall in adults with moderate-severe traumatic brain injury.Cortex; a journal devoted to the study of the nervous system and behavior · 2025
    Article
  5. Article
  6. Review
  7. Naming Ability in the Chronic Phase of Moderate-Severe Traumatic Brain Injury.American journal of speech-language pathology · 2025
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Memory for Conversation in Traumatic Brain Injury: A Feasibility Study and Preliminary Findings.Journal of speech, language, and hearing research : JSLHR · 2024
    Article
  13. Article
  14. Does Facebook Use Provide Social Benefits to Adults with Traumatic Brain Injury?Cyberpsychology, behavior and social networking · 2024
    Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Melissa C DuffDepartment of Hearing and Speech Sciences, Vanderbilt University Medical Center, Nashville, TN, United States.
Emily L MorrowDepartment of Hearing and Speech Sciences, Vanderbilt University Medical Center, Nashville, TN, United States.
Malcolm EdwardsDepartment of Hearing and Speech Sciences, Vanderbilt University Medical Center, Nashville, TN, United States.
Ryan McCurdyDepartment of Hearing and Speech Sciences, Vanderbilt University Medical Center, Nashville, TN, United States.
Sharice CloughDepartment of Hearing and Speech Sciences, Vanderbilt University Medical Center, Nashville, TN, United States.
Nirav PatelDepartment of Hearing and Speech Sciences, Vanderbilt University Medical Center, Nashville, TN, United States.
Kimberly WalshDepartment of Hearing and Speech Sciences, Vanderbilt University Medical Center, Nashville, TN, United States.
Natalie V CovingtonDepartment of Speech-Language-Hearing Sciences, University of Minnesota, Minneapolis, MN, United States.

Funding

Relational Memory as a Model of Behavioral (Dys)Function in Adults with Traumatic Brain InjuryR01NS110661 · NINDS · VANDERBILT UNIVERSITY MEDICAL CENTER · PI COHEN, NEAL J., DUFF, MELISSA C · 2020 to 2024
$3.2M
NINDS NIH HHS R01 NS110661
6 · The paper itself

Abstract

The number of individuals affected by traumatic brain injury (TBI) is growing globally. TBIs may cause a range of physical, cognitive, and psychiatric deficits that can negatively impact employment, academic attainment, community independence, and interpersonal relationships. Although there has been a significant decrease in the number of injury related deaths over the past several decades, there has been no corresponding reduction in injury related disability over the same time period. We propose that patient registries with large, representative samples and rich multidimensional and longitudinal data have tremendous value in advancing basic and translational research and in capturing, characterizing, and predicting individual differences in deficit profile and outcomes. Patient registries, together with recent theoretical and methodological advances in analytic approaches and neuroscience, provide powerful tools for brain injury research and for leveraging the heterogeneity that has traditionally been cited as a barrier inhibiting progress in treatment research and clinical practice. We report on our experiences, and challenges, in developing and maintaining our own patient registry. We conclude by pointing to some future opportunities for discovery that are afforded by a registry model.

Indexed as

heterogeneityinterventionoutcomeregistrytraumatic brain injury

Identifiers

PMID35548696
PMCPMC9082794

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.