ArticlePaediatric & neonatal pain2021
Assessment of perceived distress due to nasopharyngeal swab collection in healthy Indian infants participating in a clinical trial.
Article in Paediatric & neonatal pain, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
9 citing papers in PubMed, 13 citations in OpenAlex.
- Combined oropharyngeal nasal (ON) swabs for the molecular detection of respiratory pathogens includingMicrobiology spectrum · 2025Article
- Incremental yield in detection of TB by testing multiple stool specimens from one person.IJTLD open · 2025Article
- Factors Affecting Procedural Pain and Discomfort Experienced by Individuals During Nasopharyngeal Swabbing: A Cross-Sectional Study.Florence Nightingale journal of nursing · 2024Article
- Perceived distress due to nasopharyngeal swab collection: Correspondence.Paediatric & neonatal pain · 2024Article
- Normal saline for children with bronchiolitis: study protocol for a randomised controlled non-inferiority trial.BMJ paediatrics open · 2024Article
- Perceived distress due to nasopharyngeal swab collection: Correspondence.Paediatric & neonatal pain · 2023Article
- Efficacy of oral mefenamic acidTherapeutic advances in vaccines and immunotherapy · 2023Article
- Article
- Assessment of perceived distress due to nasopharyngeal swab collection in healthy Indian infants participating in a clinical trial.Paediatric & neonatal pain · 2021Article
Corrections and comments
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Routinely children are exposed to various procedures as a part of clinical care and/or research participation. Public health strategies to contain current COVID-19 pandemic demanded massive nasopharyngeal swab testing but limited data exist to confirm the extent of the pain and distress that result from this procedure. These data could help clinicians to formulate mitigation strategies, influence public health directives, and inform review boards/ethics committees to decide on risk-benefit ratio of the procedure. Hence, an observational study to assess perceived distress was nested in a phase IV alternate and reduced dose schedule trial of the pneumococcal conjugate vaccine (PCV) in which nasopharyngeal swab (NPS) was used to collect nasopharyngeal secretions as part of the study procedure. Out of 805 infant participants enrolled in the main study, a total of 425 infants were enrolled and observed for procedural distress at 18 weeks and 10 months of age using the Face Leg Activity Cry and Consolability (FLACC) Scale. The FLACC score and duration of cry were recorded. The mean FLACC score changed substantially from preprocedural to procedure in both age groups (from 0.08 to 5.8 at 18 weeks and from 0.5 to 7.007 at 10 months.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.