ArticleFrontiers in cardiovascular medicine2022
Echocardiographic Normal Reference Ranges for Non-invasive Myocardial Work Parameters in Pediatric Age: Results From an International Multi-Center Study.
Article in Frontiers in cardiovascular medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed.
- Myocardial work efficiency in children with Wolff-Parkinson-White preexcitation before and after accessory pathway ablation.Frontiers in cardiovascular medicine · 2026Article
- From repair to right heart failure: Understanding the evolving landscape in tetralogy of fallot.Heart failure reviews · 2025Review
- Reduced myocardial work in Fontan circulation: feasibility, reproducibility, and diagnostic performance.European heart journal. Imaging methods and practice · 2025Article
- Pediatric Echocardiographic Nomograms: Twenty Years of Advances-Do We Now Have a Complete and Reliable Tool, or Are Gaps Still Present? An Up-to-Date Review.Journal of clinical medicine · 2025Review
- Normal Values for Echocardiographic Myocardial Work in a Large Pediatric Population.Diagnostics (Basel, Switzerland) · 2024Article
- Cardiovascular function shows early impairment in asymptomatic adolescents diagnosed with type 1 diabetes mellitus: an ultrasound-derived myocardial work study.Frontiers in cardiovascular medicine · 2024Article
- The Role of Multimodality Imaging in Pediatric Cardiomyopathies.Journal of clinical medicine · 2023Review
- Normal ranges of non-invasive left ventricular myocardial work indices in healthy young people.Frontiers in pediatrics · 2022Article
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Authors and funding
15 authors.
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Abstract
Aims: This international multi-center study aimed to demonstrate the feasibility and reliability of non-invasive myocardial work (MW) parameters in the pediatric population, and to provide normal reference ranges for this useful echocardiographic tool in this specific subset of patients. Methods and Results: In this retrospective multi-center study involving three pediatric laboratories, 150 healthy children and adolescents (mean age of 10.6 ± 4.5, 91 males) were enrolled. A complete echocardiographic examination has been performed, including global longitudinal strain (GLS) assessment. The following parameters of non-invasive MW have been obtained through a dedicated software: global work index (GWI), global constructive work (GCW), global work waste (GWW), and global work efficiency (GWE), using left ventricular (LV) strain loops and non-invasive brachial artery cuff pressure values. The lowest expected values were for GWI 1,723 mmHg% in males and 1,682 mmHg% in females, for GCW 2,089 and 2,106 mmHg%, for GWE 95.9 and 95.5% whereas the highest expected value for GWW was 78 mmHg% in men and 90 mmHg% in women. The univariable and multivariable analysis showed significant associations between either GWI or GCW with SBP (β coefficient = 0.446, Conclusion: Non-invasive MW parameters were feasible and reliable in the pediatric population. This study provided normal reference ranges of these useful echocardiographic indices.
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