Evidence map›Paper›PMID 35548416›Full record

ArticleFrontiers in cardiovascular medicine2022

Romina A Di Mattía, Leandro A Díaz Zegarra, Carlos A Valverde, Paula G Blanco, Carolina Jaquenod De Giusti, Enrique L Portiansky, Ernesto A Aiello, Alejandro Orlowski

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cardiovascular medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Loss of NaActa physiologica (Oxford, England) · 2025
    Article
  2. The role of NaPflugers Archiv : European journal of physiology · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Romina A Di MattíaCentro de Investigaciones Cardiovasculares "Dr. Horacio E. Cingolani, " Facultad de Ciencias Médicas, Universidad Nacional de La Plata-CONICET, La Plata, Argentina.
Leandro A Díaz ZegarraCentro de Investigaciones Cardiovasculares "Dr. Horacio E. Cingolani, " Facultad de Ciencias Médicas, Universidad Nacional de La Plata-CONICET, La Plata, Argentina.
Carlos A ValverdeCentro de Investigaciones Cardiovasculares "Dr. Horacio E. Cingolani, " Facultad de Ciencias Médicas, Universidad Nacional de La Plata-CONICET, La Plata, Argentina.
Paula G BlancoCentro de Fisiología Reproductiva y Métodos Complementarios de Diagnóstico, Facultad de Ciencias Veterinarias, Universidad Nacional de La Plata-CONICET, La Plata, Argentina.
Carolina Jaquenod De GiustiCentro de Investigaciones Cardiovasculares "Dr. Horacio E. Cingolani, " Facultad de Ciencias Médicas, Universidad Nacional de La Plata-CONICET, La Plata, Argentina.
Enrique L PortianskyLaboratorio de Análisis de Imágenes, Facultad de Ciencias Veterinarias, Universidad Nacional de La Plata-CONICET, La Plata, Argentina.
Ernesto A AielloCentro de Investigaciones Cardiovasculares "Dr. Horacio E. Cingolani, " Facultad de Ciencias Médicas, Universidad Nacional de La Plata-CONICET, La Plata, Argentina.
Alejandro OrlowskiCentro de Investigaciones Cardiovasculares "Dr. Horacio E. Cingolani, " Facultad de Ciencias Médicas, Universidad Nacional de La Plata-CONICET, La Plata, Argentina.
Consejo Nacional de Investigaciones Científicas y Técnicas · ARUniversidad Nacional de La Plata · ARCentro de Investigaciones Cardiovasculares · AR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cardiac cells depend on specific sarcolemmal ion transporters to assure the correct intracellular pH regulation. The sodium/bicarbonate cotransporter (NBC) is one of the major alkalinizing mechanisms. In the heart two different NBC isoforms have been described: the electroneutral NBCn1 (1Na

Indexed as

action potentialadeno-associated virus (AAV)ECGmiceNBCe1

Identifiers

PMID35548416
PMCPMC9082548
OpenAlexW4224441301

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.