Evidence map›Paper›PMID 35548213›Full record

ArticleRSC advances2018

Titanium dioxide nanoparticles induce mitochondria-associated apoptosis in HepG2 cells.

Zhenglin Xia, Jingliang He, Bowei Li, Ke He, Wenbing Yang, Xiaoxun Chen, Jinqian Zhang, Guoan Xiang

RetractedOpen access · goldAbstract readRetracted Publication
In one paragraph

Article in RSC advances, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.7field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 23 citations in OpenAlex.

  1. Article
  2. Hierarchical TiOJournal of the Royal Society, Interface · 2025
    Article
  3. Hepatotoxicity of titanium dioxide nanoparticles.Journal of applied toxicology : JAT · 2025
    Review
  4. Article
  5. Review
  6. Article
  7. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Zhenglin XiaDepartment of General Surgery, Guangdong Second Provincial General Hospital, Southern Medical University Guangzhou 510515 People's Republic of China guoan_66@163.com.ORCID https://orcid.org/0000-0001-8671-4458
Jingliang HeShunde Hospital of Guangzhou University of Chinese Medicine Foshan 528300 People's Republic of China.
Bowei LiDepartment of General Surgery, Guangdong Second Provincial General Hospital, Southern Medical University Guangzhou 510515 People's Republic of China guoan_66@163.com.
Ke HeDepartment of General Surgery, Guangdong Second Provincial General Hospital, Southern Medical University Guangzhou 510515 People's Republic of China guoan_66@163.com.
Wenbing YangDepartment of General Surgery, The Second Affiliated Hospital of Xi'an Jiao Tong University Xi'an 710004 People's Republic of China.
Xiaoxun ChenDepartment of Gastrointestinal Surgery, The Guigang City People's Hospital Guigang Guangxi 537100 People's Republic of China.
Jinqian ZhangDepartment of Laboratory Medicine, Guangdong Second Provincial General Hospital, Southern Medical University Guangzhou 510515 People's Republic of China jingwanghou@163.com.ORCID https://orcid.org/0000-0003-0765-1183
Guoan XiangDepartment of General Surgery, Guangdong Second Provincial General Hospital, Southern Medical University Guangzhou 510515 People's Republic of China guoan_66@163.com.
State Council of the People's Republic of China · CNGuangzhou University of Chinese Medicine · CNGuigang City People's Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Widespread applications of nanosized materials over the past decade have prompted investigations of desirable properties and potential hazards to humans and the environment. Titanium dioxide (TiO

Identifiers

PMID35548213
PMCPMC9085782
OpenAlexW2891964618

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.