Evidence map›Paper›PMID 35548210›Full record

ArticleRSC advances2018

Mitochondria targeting IR780-based nanoGUMBOS for enhanced selective toxicity towards cancer cells.

Mi Chen, Nimisha Bhattarai, Mingyan Cong, Rocío L Pérez, Karen C McDonough, Isiah M Warner

Abstract read
In one paragraph

Article in RSC advances, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Mi ChenDepartment of Chemistry, Louisiana State University Baton Rouge LA 70803 USA iwarner@lsu.edu.
Nimisha BhattaraiDepartment of Chemistry, Louisiana State University Baton Rouge LA 70803 USA iwarner@lsu.edu.
Mingyan CongDepartment of Chemistry, Louisiana State University Baton Rouge LA 70803 USA iwarner@lsu.edu.
Rocío L PérezDepartment of Chemistry, Louisiana State University Baton Rouge LA 70803 USA iwarner@lsu.edu.
Karen C McDonoughAgCenter Biotechnology Labs, Louisiana State University Baton Rouge LA 70803 USA.
Isiah M WarnerDepartment of Chemistry, Louisiana State University Baton Rouge LA 70803 USA iwarner@lsu.edu.ORCID https://orcid.org/0000-0002-5336-7653

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Herein, a simple counter-ion variation strategy is proposed and demonstrated for design of an array of near infrared IR780-based nanoGUMBOS (nanomaterials from a Group of Uniform Materials Based on Organic Salts) to produce enhanced anticancer activity. These nanomaterials were synthesized by direct nanoengineering of IR780-based GUMBOS using a reprecipitation method, without addition of any other materials. Thus, these novel nanomaterials can serve as carrier-free nanodrugs, providing several distinct advantages over conventional chemotherapeutics. Examination of the size and stability of these nanoGUMBOS indicates formation of approximately 100 nm nanoparticles that are stable under biological conditions. Interestingly,

Identifiers

PMID35548210
PMCPMC9085727

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.