ArticleRSC advances2018
The synthesis of HMF-based α-amino phosphonates
Article in RSC advances, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
6 citing papers in PubMed.
- Brønsted Acid-Catalyzed Multicomponent Phosphonylation/Cyclization Strategy for the Synthesis of Phosphinylated 2ACS omega · 2026Article
- C2 to C6 biobased carbonyl platforms for fine chemistry.Beilstein journal of organic chemistry · 2025Review
- Synthesis of α-Aminophosphonates and Related Derivatives; the Last Decade of the Kabachnik-Fields Reaction.Molecules (Basel, Switzerland) · 2021Review
- Phosphonates enantiomers receiving with fungal enzymatic systems.Microbial cell factories · 2021Review
- Nanostructured N doped TiORSC advances · 2020Article
- Direct Synthesis of Phosphonates and α-Amino-phosphonates from 1,3-Benzoxazines.Molecules (Basel, Switzerland) · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The first use of biomass-derived HMF in the one-pot Kabachnik-Fields reaction is reported here. A wide range of furan-based α-amino phosphonates were prepared in moderate to excellent yields under mild, effective and environmentally-benign conditions: iodine as a non-metal catalyst, biobased 2-MeTHF as the solvent and room or moderate temperature. The hydroxymethyl group of HMF persists in the Kabachnik-Fields products, widening the scope of further modification and derivatization compared to those arising from furfural. Issues involving the diastereoselectivity and double Kabachnik-Fields condensation were also faced.
Identifiers
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Registered trials
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